It is well known that most schizophrenia patients smoke cigarettes. There are different hypotheses postulating the underlying mechanisms of this comorbidity. We used summary statistics from large meta-analyses of plasma cotinine concentration (COT), Fagerström test for nicotine dependence (FTND) and schizophrenia to examine the genetic relationship between these traits. We found that schizophre...

This paper presents the PLS genetic algorithm segmentation methodology which uses directed random searches to detect an optimum solution in the complex search space that underlies data partitioning tasks in PLS path modeling. The results of a simulation study allow a primary assessment of this novel approach and reveal its capabilities and effectiveness. Furthermore, applying the approach to th...

Two GRMs were fitted using the method created by Zaitlen et al (2013). The first GRM comprised of pairwise relationship coefficients of all individuals in the sample. The second GRM included off-diagonal elements of pairs of individuals who has a relationship coefficient < 0.05 set to 0. Assuming inbreeding had not taken place, the second GRM excluded pairs of individuals with a most recent com...

background: hla genes are highly polymorphic and certain alleles are frequent only in specific populations. therefore, hla is a unique tool for studying the genetic relationship between different populations. iranians are ethnically diverse people and one of the major ethnic groups in iran is lur population inhabiting along the central and southern parts of zagros chain mountain. objectives: ge...

Despite the fact that the continuity of morphology of fossil specimens of modern humans found in China has repeatedly challenged the Out-of-Africa hypothesis, Chinese populations are underrepresented in genetic studies. Genetic profiles of 28 populations sampled in China supported the distinction between southern and northern populations, while the latter are biphyletic. Linguistic boundaries a...

There is a long history of opposition to allowing parents to use biotechnology in order to select the traits of their children. Jurgen Habermas’s book, The Future of Human Nature, is an important addition to this literature. Habermas, like C.S. Lewis and Paul Ramsey before him, is concerned that children’s futures are fixed by parental choices and that genetic selection or modification treats c...

Fulani ecotype chickens (FEC) and Yoruba ecotype chickens (YEC) are the two major types of indigenous chickens in Nigeria. They subsist under traditional Animal husbandry and are thus liable to indiscriminate mating and consequently to loss of genetic diversity. Fulani ecotype chickens (FEC) and Yoruba ecotype chickens (YEC) were investigated to determine genetic variation at transferrin locus ...

having knowledge about genetic relationships among accessions is necessary for developing breeding strategies to produce improved cultivars. in present study, genetic diversity and inter-relationship among 29 genotypes of citrus were comparatively analyzed using morphological and rapd markers. significant variability was observed among citrus genotypes for 61 quantitative and qualitative morpho...