We construct a zig-zag process targeting posterior distributions arising in genetics from the Kingman coalescent and several popular models of mutation. show that can lead to efficiency gains up orders magnitude over classical Metropolis-Hastings, argue it is also well suited parallel computation for models. Our construction based on embedding discrete variables into continuous space; technique...

introduction: physicians have to visit, diagnose and refer patients with genetic disorders, so they need to be familiar with the basics and indications of genetic tests. in other words, they should have effective theoretical and practical knowledge about medical genetics before they do their job. medical genetics courses at medical universities of iran are generally presented as a theoretical s...

conclusions il6 and il8 gene polymorphisms have no role in nash pathogenesis and liver fibrosis process, but presence of the a/a genotype in the il8 gene is associated with disease progression. patients and methods consecutive patients with biopsy proven nash and age- and gender-matched healthy individuals with normal liver function tests and normal ultrasonography were enrolled in the study. h...

background: the goal of the present work was to determine frequencies of different finger patterns of a population in hamadan (one of the western cities of iran) in 1997. methods: in a cross-sectional study, the .prints of the first phalanx of both hands of 717 randomly selected hamadan students (i88 men, 529 women) have taken, by using standard method (stamp ink). the fingerprints were classif...

Data mining is the process of extracting useful unknown knowledge from large datasets. Frequent itemset fundamental task data that aims at discovering interesting itemsets frequently appear together in a dataset. However, infrequent (rare) may be more many real-life applications such as predicting telecommunication equipment failures, genetics, medical diagnosis, or anomaly detection. In this p...

background:in the recent decade, the reverse genetics method has been broadly used for rescue of negative-stranded rna viruses from cdna or viral minigenomes. this technique has been applied to study different steps in virus replication and virus-host interactions. reverse genetics could also be implemented for design of new vaccines. the t7 rna polymerase activity as well as virus (nucleocapsi...