Submit Manuscript | http://medcraveonline.com Abbreviations: AGEs: Advanced Glycation End-products; ROS: Reactive Oxygen Species; DM: Diabetes Mellitus; RAGE: Receptors of AGEs; HLA: Human Leucocyte Antigen; GDM: Gestational Diabetes Mellitus; MODY: Maturity Onset Diabetes of the Young; SMBG: Self Monitoring Blood Glucose; HAS: Human Serum Albumin; HMA: Human Mercaptalbumin; PCO: Protein Carbon...

Women with a history of gestational diabetes mellitus (GDM) are known to be at increased risk for diabetes and cardiovascular disease. Other cardiovascular risk factors that integrate the metabolic syndrome also seem to be more prevalent in this group of women. On the other hand, several studies have shown that there is an ethnic effect on disease risk. Prevalence of type 2 diabetes, gestationa...

Diabetes mellitus is a group of diseases characterized by chronic hyperglycemia. Women who develops hyperglycemia for the first time during pregnancy receive the diagnosis gestational diabetes mellitus (GDM). Presently, there is no consensus about the diagnostic criteria for GDM. A majority of these women subsequently develop postpartum overt diabetes making it important to identify these patie...

OBJECTIVES Circulating Fibroblast Growth Factor 21 (FGF21) levels are increased in insulin resistant states such as obesity, type 2 diabetes mellitus and gestational diabetes mellitus (GDM). In addition, GDM is associated with serious maternal and fetal complications. We sought to study human cerebrospinal fluid (CSF) and corresponding circulating FGF21 levels in women with gestational diabetes...

BACKGROUND The frequency of gestational diabetes mellitus (GDM) is 0.6% -15% of pregnant woman. The modern trend towards the delay starting family is the main factor responsible for increase prevalence of GDM. This condition is associated with the adverse effect on mother and fetus, so it is important to find out the GDM by screening of all the pregnant women. OBJECTIVE To observe the feasibi...

objective: this study evaluated the efficacy and safety of metformin on prevention of gestational diabetes mellitus in women with high risk of gdm. materials and methods: total number of 189 pregnant women aged between 25 to 35, and 10 to 14 weeks pregnancy,admitted to  mirza koochakkhan hospital, tehran in january 2008 - january 2009 entered to this randomized controlled clinical trial. the wo...

Background Studies have shown that maternal obesity is associated with increased risk of Gestational Diabetes Mellitus (GDM). When compared to normal weight women, the chance of developing the disease steadily increases in those who are overweight, obese and severely obese. Excessive gestational weight gain is also associated with risk of GDM. Moreover, dietary factors, before and during pregna...

BACKGROUND The outbreak of gestational diabetes has a significant increase during recent years. This disease has complications for mother and her baby. Screening is an opportunity for preventing of gestational diabetes complications. OBJECTIVE The aim of this research was to determine the most important risk factors for Gestational Diabetes Mellitus (GDM) in Iran according to the expert's vie...

Gestational diabetes mellitus (GDM) is defined as the glucose intolerance that is not present or recognized prior to pregnancy. Several risk factors of GDM depend on environmental factors that are thought to regulate the genome through epigenetic mechanisms. Thus, epigenetic regulation could be involved in the development of GDM. In addition, the adverse intrauterine environment in patients wit...