Background: Gingival overgrowth is a common clinical finding that most often represents reactive hyperplasia as a result of inflammatory gingival disease related to dental plaque. Irritation fibroma (IF), pyogenic granuloma (PG), peripheral ossifying fibroma (POF), and peripheral giant cell granuloma (PGCG) are non-neoplastic enlargements of the gingiva that are categorized as reactive hyperpla...

AIMS Tacrolimus and Cyclosporine A (CyA) are cornerstones in immunosuppressive therapy. Cyclosporine side eff ects include hypertension and hypercholesterolemia both of which may increase the risk of cardiovascular mortality, gingival hyperplasia and hirsutism are known to reduce quality of life. The aim of this prospective study was to evaluate changes in cardiovascular risk profile and cosmet...

leukemia is a neoplastic disease with early oral and periodontal manifestations such as ulceration, infection, bleeding and gingival hyperplasia. this paper describes a 39-year-old pregnant woman with a diagnosis of acute myelomonocytic leu-kemia (aml), with gingival enlargement in the upper and lower jaws. a gingival biopsy was performed, followed by a complete blood count and peripheral blood...

Cyslosporin A (CyA) treatment of psoriasis is warranted in severe cases where other, conventional antipsoriatic approaches have failed. Gingival hyperplasia is a rare side effect of cyclosporin A treatment in psoriasis patients. Previous studies in cyclosporin A-treated patients (mostly transplant recipients) have demonstrated correlation between cyclosporin A serum levels and oral hygiene stat...

OBJECTIVE Long-term use of phenytoin (PHT) causes gingival hyperplasia; however, little is known about the oral side effects of other antiepileptic drugs (AEDs). Through a systematic review of the literature, we explored the effects of AEDs on the oral health of patients with epilepsy. METHODS We searched PubMed, EMBASE and the Cochrane library between January 1963 and August 2010. The search...