Glucocorticoid (GC) induced osteoporosis (GIO) is caused by the long-term use of GC for treatment of autoimmune and inflammatory diseases. The GC related disruption of bone marrow microcirculation and increased adipogenesis contribute to GIO development. However, neither currently available anti-osteoporosis agent is completely addressed to microcirculation and bone marrow adipogenesis. Salvian...

Vertebral fractures are an under-recognized problem in children with glucocorticoid-induced osteoporosis (GIO). They cause severe back pain and spinal column deformity with a decrease of quality of life. For evaluating the bone mass, bone mineral density measurements have been widely carried out using dual energy X-ray absorptiometry. However, bone histomorphometric analyses of GIO in children ...

Matrix fixed-point iterations zn+1 = ψ(zn) defined by a rational function ψ are considered. For these iterations a new proof is given that matrix convergence is essentially reduced to scalar convergence. It is shown that the principal Padé family of iterations for the matrix sign function and the matrix square root is a special case of a family of rational iterations due to Ernst Schröder. This...

Hierarchical Graph Transformation Gio r g i o Bu s a t t o Carl v. Ossietzky Universität Fachbereich Informatik 26111 Oldenburg email: [email protected] Han s J ö r g K r e ow sk i, S ab i n e Ku sk e University of Bremen Department of Computer Science P.O. Box 330440 D-28334 Bremen email: {kreo,kuske}@informatik.uni-bremen.de

The Royal Society expedition to Antarctica established a base at Halley Bay, in support of the International Geophysical Year of 1957–1958. Surface ozone was measured during 1958 only, using a prototype Brewer-Mast sonde. The envelope of maximum ozone was an annual cycle from 10 ppbv in January to 22 ppbv in August. These values are 35% less at the start of the year and 15% less at the end than...

for dissemination) In the last twelve years since Gio Wiederhold [Wiederhold, 1992] first came up with the idea of mediation and mediation systems, intensive research has been done in this field. In this report, we provide an overview of the current state-of-the-art in data, information, and processes mediation and an analysis of the requirements for constructing a mediation system.

Further to the proposal and application of a stochastic methodology and the resulting first exit time distribution function to life table data we introduce a theoretical framework for the estimation of the maximum deterioration age and to explore on how “vitality,” according to Halley and Strehler and Mildvan, changes during the human lifetime. The mortality deceleration or mortality leveling-o...