نتایج جستجو برای: glanzmanns thrombasthenia
تعداد نتایج: 525 فیلتر نتایج به سال:
Glanzmann thrombasthenia is a rare bleeding disorder that can present life-threatening bleeding. Our patients develop antiplatelet antibodies that become refractory to any pharmacological treatment. Allogeneic hematopoietic stem-cell transplantation is the only currently curative procedure, but has major risks mainly in adult; indeed, our patient died.
BACKGROUND Glanzmann thrombasthenia (GT) is a rare inherited platelet disorder that is characterized by spontaneous or postprocedural bleeding. The diagnosis of GT depends on identifying the dysfunction of the platelets. AIM The aim of this study was to compare a whole blood impedance Multiplate analyzer (MEA) with the standard method, light transmission aggregometry (LTA) in diagnosis of GT....
Cultures of established and transformed fibroblasts were less able to contract a hydrated collagen gel than normal precrisis cells. Postcrisis fibroblasts from different rodent strains and species underwent a further reduction in contraction ability and either spontaneous or simian virus 40 (SV40) transformation. Human precrisis fibroblasts contracted much more efficiently than two SV40-transfo...
glanzmann's thrombasthenia (gt) is a rare, genetically inherited platelet disorder in which the platelet glycoprotein iib/iiia (gp iib/iiia) complex is either deficient or, dysfunctional. the incidence is about 1 in 1,000,000. this case report deals with a 4 year-old girl diagnosed with gt presenting with dental caries and periapical lesions in the primary mandibular first molars. to provide th...
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