Background: Elevated intraocular pressure (IOP) is one of the most important factors for diagnosis and monitoring glaucoma. IOP currently only modifiable risk factor glaucoma, cornea transparent tissue covering front eye. It a powerful refracting surface, providing 2/3 eye's focusing power. The adult about 1/2 millimeter thick comprised 6 layers: epithelium, Bowman's membrane, stroma, Dua's lay...

PURPOSE To describe the diurnal variation of the ocular perfusion pressure (OPP) in normal, suspects and glaucoma patients. MATERIALS AND METHODS Seventy-nine subjects were enrolled in a prospective study. The diurnal curve of intraocular pressure (IOP) was performed and blood pressure measurements were obtained. Each participant was grouped into one of the following based upon the clinical e...

BACKGROUND To investigate large cup-to-disc ratios (CDR) in children and to determine the relationship between parental CDR and clinical characteristics associated with glaucoma. METHODS Two hundred thirty six children aged 6 to 12 years with CDR ≥ 0.6 were enrolled in this study. Subjects were classified into two groups based on parental CDR: disc suspect children with disc suspect (CDR ≥0.6...

PURPOSE To understand the factors that influence glaucoma treatment adherence with medication taking, prescription refills, and appointment keeping to develop an intervention for a specific population. PATIENTS AND METHODS In-depth interviews were conducted with 80 individuals diagnosed with open-angle glaucoma, glaucoma suspect, or ocular hypertension. Additional eligibility requirements wer...

Material and Methods: This study was conducted in ophthalmology department PNS Shifa, Karachi. From March 2013 to Jan 2015 for 23 months. A total of 350 glaucoma suspect patients were selected. A detailed history of ocular or systemic diseases was taken. Intraocular pressure (IOP) was measured using Goldmann Applanation tonometer. Optical Coherence Tomography (OCT) images were taken using Heide...

PURPOSE To develop a new three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) data analysis method using a machine learning technique based on variable-size super pixel segmentation that efficiently utilizes full 3D dataset to improve the discrimination between early glaucomatous and healthy eyes. METHODS 192 eyes of 96 subjects (44 healthy, 59 glaucoma suspect and 89 ...