 Of those included, 47.2% were adults, 69.3% had HA and 61.5% had severe hemophilia (HA N=151, HB N=47). Significantly fewer individuals on prophylaxis vs. on-demand treatment were adults, had HB or had mild/moderate hemophilia. (Table 1)  An ABR of 1-10 was recorded in 58% of participants. A higher percentage of adults vs. children with severe hemophilia had ABR ≥11 among those treating on-d...

• Quantity of annual carbon sequestration by terrestrial ecosystems can be measured at a reasonable accuracy; • Median measure of current NEP or sequestration by forested ecosystems is 3 metric tons per hectare per year; • Current calculated global TBCS for forests is ~3Gt C per yr; • Estimated future TBCS capacity is 200-250 Gt C using available knowledge and current technology and management ...

Background and Objectives: Ethiopia’s food insecurity will increase unless it can dramatically boost agricultural productivity. In 1993, the Sasakawa/Global 2000 Program (SG) and the Ministry of Agriculture (MOA) began a joint program to demonstrate that substantial productivity increases could be achieved when farmers were given appropriate extension messages and agricultural inputs were deliv...

In their Perspective in this issue of PLOS Biology, Blomqvist et al. [1] set out to demonstrate that ‘‘Ecological Footprint measurements, as currently constructed, are so misleading as to preclude their use in any serious science or policy context.’’ Should the reader be confident in this assessment or are Ecological Footprint methods and results adequate to guide sustainability policy? Their P...

Urban population scaling of resource use, creativity metrics, and human behaviors has been widely studied. These studies have not looked in detail at the full range of human environments which represent a continuum from the most rural to heavily urban. We examined monthly police crime reports and property transaction values across all 573 Parliamentary Constituencies in England and Wales, findi...

The relationships between basic and applied agricultural R&D, developed and developing country R&D and between R&D, extension, technology and productivity growth are outlined. The declining growth rates of public R&D expenditures are related to output growth and crop yields, where growth rates have also fallen, especially in the developed countries. However, growth in output value per hectare h...

China is facing intense coastal eutrophication. Large-scale seaweed aquaculture in China is popular, now accounting for over 2/3's of global production. Here, we estimate the nutrient removal capability of large-scale Chinese seaweed farms to determine its significance in mitigating eutrophication. We combined estimates of yield and nutrient concentration of Chinese seaweed aquaculture to quant...

In a 3-yr study, 135 crossbred steers (330 ± 10 kg) were used in a randomized complete block design to evaluate corn dried distillers grains plus solubles (DDGS) fed to yearling steers as a substitute for forage and N fertilizer and its effect on N use efficiency in yearling steers grazing smooth bromegrass pastures. Steers were initially stocked at 6.8 animal unit months (AUM)/ha on nonfertili...