OBJECTIVE To examine the associations of maternal gestational glucose tolerance with offspring body composition in late childhood. RESEARCH DESIGN AND METHODS Among 958 women in the prebirth cohort Project Viva, glucose tolerance was assessed in the second trimester by nonfasting 50-g 1-h glucose challenge test (GCT), followed if abnormal by fasting 100-g 3-h oral glucose tolerance test (OGTT...

background: vitamin d deficiency is common in pregnancy, leading to increase in the frequency of preeclampsia, cesarean delivery, neonatal bacterial vaginosis, and gestational diabetes. the current study was designed and implemented to investigate the effect  of vitamin d during the first and second trimesters of pregnancy in reducing the risk of gestational diabetes mellitus (gdm) in women who...

OBJECTIVE An association between maternal hypoglycemia during pregnancy with fetal growth restriction and overall perinatal mortality has been reported. In a retrospective pilot study we found that hypoglycemia was linked with a greater number of special care/neonatal intensive care unit admissions and approached significance in the number of women who developed preeclampsia. That study was lim...

The prediction of birth weight may be improved by the measurement of hormones or growth factors in the mother. We measured body weight (BW) and plasma levels of placental GH (PGH), IGF-I, IGF-binding protein-1 (IGFBP-1), and leptin at the time of the glucose challenge test (GCT) in 289 women, who were pregnant with a single fetus, between 24 and 29 wk gestational age (GA). Delivery occurred 12 ...

OBJECTIVE To compare perinatal outcome of women after third trimester oral glucose tolerance test (GTT) following normal glucose challenge test (GCT) stratified by test results. STUDY DESIGN Retrospective cohort study of women delivered in a tertiary, university affiliated medical center (2007-2012). Inclusion criteria were women with a normal 50 g GCT (<140 mg/dl) followed by GTT, who delive...

AIM To elucidate an evidence based Single Glucose Challenge test to diagnose Gestational Diabetes Mellitus (GDM). METHOD This study included 500 pregnant women in 16-32 weeks of gestation. They underwent 75g Oral Glucose Challenge test irrespective of the last meal timing and 2 hr venous blood was drawn. After 3 days they underwent 75g OGTT in the fasting state and their 2 hr blood was drawn....

The latest criteria on diagnosis and classification of diabetes mellitus [1] were recently published in Diabetes Care. In the section on GDM, the controversy over the one-step/ two-step testing has resurfaced as expected after the NIH consensus statement [2]. One of the reported key factors in NIH decision-making process to favor two-step testing over the one-step IADPSG criteria was that scree...

BACKGROUND Maternal hyperglycemia is considered a risk factor for fetal morbidity. Since there is a high prevalence of diabetes mellitus among the population of Bahrain, we conducted a prospective population-based study of gestational diabetes mellitus (GDM) in non-diabetic pregnant women. SUBJECTS AND METHODS All non-diabetic pregnant women attending antenatal clinics during January 2001 to ...

BACKGROUND Gestational diabetes mellitus (GDM) is common problem during pregnancy. Diagnostic criteria of this problem are based on foreign population. Because of differences in racial, cultural, and nutritional characteristics, we need to determine these criteria are suitable for Iranian population. OBJECTIVE To determine whether different diagnostic criteria of gestational diabetes mellitus...