To establish normative data and determine the value of fluorometric AutoDELFIA assays (Wallac Oy) in the investigation of precocious puberty, we determined serum levels of LH, FSH, testosterone, and estradiol under basal and GnRH-stimulated conditions in 277 normal subjects at various pubertal stages and in 77 patients with precocious puberty. A substantial overlap was observed in basal and GnR...

BACKGROUND Achieving pregnancy by in vitro fertilization (IVF) treatment depends on many factors, including the ovaries' capacity and the efficiency of ovarian stimulation. The aim of this study was to assess the influence of ovarian stimulation with human and recombinant gonadotropin, as well as specific hormonal parameters, on the effectiveness of IVF and the dynamics of embryonic development...

background: to assess the usefulness of premature luteinization hormone (lh) surge prevention in an intrauterine insemination (iui) cycle by gnrh antagonist administration materials and methods: sixty patients with unexplained or mild male infertility or minimal to mild endometriosis were enrolled in this prospective randomized controlled trial. there were twenty patients in group a (with gnrh ...

A better understanding of interindividual differences and the development targeted therapies is one major challenges modern medicine. The sex a person plays crucial role in this regard. This systematic review aimed to summarise analyse available evidence on mutual interactions between non-invasive brain stimulation sex/polypeptide hormones. PubMed database was searched from its inception 31 Mar...

To determine the effect of local endometrial injury on implantation success in patients diagnosed with unexplained infertility and undergoing intrauterine insemination (IUI) after ovulation induction gonadotropins. In this prospective randomized controlled trial, 82 infertile underwent IUI following gonadotropin. study group (n:40), (stratch) was performed to posterior side cavity a biopsy cath...

Background To assess the usefulness of premature luteinization hormone (LH) surge prevention in an intrauterine insemination (IUI) cycle by GnRH antagonist administration MaterialsAndMethods Sixty patients with unexplained or mild male infertility or minimal to mild endometriosis were enrolled in this prospective randomized controlled trial. There were twenty patients in group A (with GnRH anta...

BACKGROUND Poor ovarian response to controlled ovarian stimulation is one of the most important interest points in assisted reproduction. Mild ovarian stimulation seems to be preferable to high dose of FSH regimens in women with a history of poor ovarian response in previous protocol. Clomiphene citrate and letrozole alone or in combination with FSH have been used in mild ovarian stimulation pr...

BACKGROUND Our objective was to evaluate the effectiveness of clomiphene citrate (CC) vs. letrozole (L) plus human menopausal gonadotropin (hMG) in gonadotropin releasing hormone (GnRH) antagonist protocol in poor prognosis women with previous failed ovarian stimulation undergoing intracytoplasmic sperm injection (ICSI). MATERIALS AND METHODS This retrospective cohort study included cycles wi...

pituitary suppression by depot gnrh agonist may be excessive for ovarian stimulation. this study compares the efficacy of a single half-dose depot triptorelin and reduced-dose daily buserelin in a long protocol icsi/et. methods: a total of 182 patients were randomized into two groups using sealed envelopes. pituitary desensitization was obtained in group 1 (91 patients) with half-dose (1.87 mg)...