background & aim: the most common primary brain tumors of the central nervous system are gliomas. among a number of different biomolecular events, a strong relation between oxidative stress pathways and the development of this cancer has been proved. oxidative stress (os) is the consequence of an imbalance between pro-oxidants and antioxidants towards pro-oxidants. the pro-oxidants cause lipid ...

Grade estimation is one of the most complicated aspects in mining. It also happens to be one of the most important. The complexity of grade estimation originates from scientific uncertainty, common to similar engineering problems, and the necessity for human intervention. The combination of scientific uncertainty and human judgement is common to all grade estimation procedures regardless of the...

This study tried to examine EFL translators’ uncertainty and uncertainty management strategies through employing think aloud procedures. The participants of this study were some MA andBA translators selected from several universities in Iran. To this aim, a proficiency test was firstly administered among the volunteers. Then, think aloud protocol and retrospective interview were used to collect...

OBJECTIVE Practice patterns vary across Canada with respect to indications for surgical staging and adjuvant radiotherapy in early endometrial cancer. We evaluated the cost-effectiveness of two common strategies for managing early endometrial cancer as part of an Ontario population-based study. METHODS A decision-analytic model (DATA 4.5) was developed for Stage I and II endometrioid-type can...

Nowadays, kriging has been accepted as the most common method of grade estimation in mineral resource evaluation stage. Access to the crisp assay data and a variogram model are the necessary means for the utilization of this method. Since fitting a crisp variogram model is generally difficult, if not impossible, the fitted theoretical model is usually tainted with uncertainty due to various rea...

To reduce treatment of indolent prostate cancer (PCa), biomarkers are needed to improve identification of patients with a low-risk of having aggressive disease. Over-treatment of these patients occurs because of uncertainty in the aggressiveness of the entire tumor based on the biopsies, which do not accurately sample multifocal tumors. Circulating microRNAs (miRNAs) are stable serum markers an...

There is still uncertainty and confusion over which grades of doctor are encompassed by the title ‘nonconsultant career grade doctors’ (NCCG). They are staff grade doctors and the more senior associate specialists. Also included are doctors working in the community, previously called clinical medical officers (CMOs) and senior clinical medical officers (SCMOs), although doctors in these groups ...

In the flotation process, the concentrate grade and the tailing grade are crucial technical indices which reflect the product quality and efficiency. There are strong nonlinearity and uncertainty in such technical indices dynamic behaviors, which can hardly be described using accurate mathematical model. The technical indices which cannot be measured online continuously vary with boundary condi...

Long-term production planning design is a major step in mine planning, because it determines the economic outcome of a project. Also long-term planes act as a guide for medium and short-term production scheduling. Because there are a large number of blocks within the ultimate pit limit, the pit can be divided into a series of sub-pits commonly called push backs, cut backs or phases. These push ...