Understanding the factors that influence N → S acyl transfer in native peptide sequences, and discovery of new reagents that facilitate it, will be key to expanding its scope and applicability. Here, through a study of short model peptides in thioester formation and cyclisation reactions, we demonstrate that a wider variety of Xaa-Cys motifs than originally envisaged are capable of undergoing e...

The advent of digital information technology heralded the concept of information warfare. This ‘preliminary’ stage in the 1990s really consisted of technology warfare where the networks, upon which combat relied, were seen as weapons to gain ‘information superiority’. This was the inception of the technological aspect of Information Warfare. The realisation of ...

With the start of 2016, we at the journal would like to wish all our readers, reviewers and Editorial Board members a most happy and prosperous new year. Ushering in this year, the journal has made some considerable changes. For one, the journal has been renamed Scoliosis and Spinal Disorders. We feel that with the ever-changing landscape of spinal conditions as well as health-care utilization ...

Several authors have shown how communication using digital devices influences the experience of psychological distance. For instance, the hyperaccessibility associated with mobile phones reduces the felt distance between people who are separated by geographical space (Cummings et al., 2001; Sommer, 2002; Turkle, 2006; Katz and Byrne, 2013). This paper discusses how interpersonal distance, i.e.,...