Previous literature suggests that the recurrence of focal segmental glomerulosclerosis (FSGS) after renal transplantation is more common in recipients who have received an HLA-identical living-related (LRD) transplant. To address the question if FSGS patients can safely receive a 6-antigen match LRD kidney transplant, we analyzed death-censored renal allograft survival data of FSGS patients fro...

Background/objective In anatomic double-bundle anterior cruciate ligament reconstruction, it is crucial to create two separate bone tunnels within the footprints of the anterior cruciate ligament at the femur and tibia. This can occasionally be difficult to accomplish and the adverse effects of bone tunnel communication are unclear. The purpose of this study was to examine the effects of intrao...

INTRODUCTION Interference screws used in fixation of anterior cruciate ligament (ACL) hamstring grafts create mechanical hold by forcing the graft into frictional contact with the bone tunnel. We analyzed the resultant graft-tunnel contact pressure using an in vitro model of human cadaver 8mm hamstring grafts. METHODS Contact characteristics were assessed using both pressure sensitive films a...

background: ligament reconstruction is a common procedure in orthopedic surgery. although several popular techniques are currently in use, new methods are proposed for secure fixation of the tendon graft into the bone tunnel. purposes: we sought to introduce our new technique of bashti bone plug for fixation of soft tissue graft in anterior cruciate ligament (acl) reconstruction and to compare ...

BACKGROUND The purpose of this study was to determine the tibial fixation strength provided by different intraosseous soft tissue graft lengths within the tibial tunnel. METHODS Porcine tibial bones and digital flexor tendons were used for testing. Bone mineral densities of proximal tibial medial condyles were measured, and two-strand tendon bundles of 8 mm diameter were used. An intraosseous...

HYPOTHESIS Recipients of 0 HLA mismatch kidneys with prolonged cold ischemia times of longer than 36 hours do not have superior outcomes compared with recipients of kidneys with 1 or more mismatches. DESIGN Retrospective review. SETTING Transplanation centers. PATIENTS AND METHODS A total of 63,688 recipients who underwent transplantation between January 1, 1990, and July 31, 1998. MAIN...

PURPOSE Extensive tunnel expansion in hamstring anterior cruciate ligament (ACL) reconstruction can complicate revision surgery. The purpose of this study was to examine our hypothesis that compaction of a bone dowel into the tibial tunnel reduces the cross-sectional area of the tunnel on the day of surgery and limits tunnel expansion to that of the cross-sectional area of the reamer at 4 month...

BACKGROUND Successful engraftment of hematopoietic stem cells from unrelated donors is influenced by disparities between the donor and recipient for HLA-A, B, and C alleles. Disparities between HLA sequence polymorphisms that are serologically detectable are termed antigen mismatches, whereas those that can be identified only by DNA-based typing methods are termed allele mismatches. Whether bot...

Ligament graft fixation with bioabsorbable interference screws is a standard procedure in cruciate ligament replacement. Previous screw designs may resorb incompletely, and can cause osteolysis and sterile cysts despite being implanted for several years. The aim of this study was to examine the in vivo degradation and biocompatibility of the new Milagro interference screw (Mitek, Norderstedt, G...