A rare clinical isolate of Streptococcus pneumoniae, highly resistant to telithromycin, contained erm(B) with a truncated leader peptide and a mutant ribosomal protein L4. By transformation of susceptible strains, this study shows that high-level telithromycin resistance is conferred by erm(B), wild type or mutant, in combination with a (69)GTG(71)-to-TPS mutation in ribosomal protein L4.

Evidence is increasing that defective metabolism of postprandial remnants of triglyceride-rich lipoproteins contributes to atherogenesis. In obesity, postprandial lipemia is increased by mechanisms that are not currently established. In the present study, a recently developed (13)CO(2) breath test was used to assess the metabolism of chylomicron remnants (CR) in obese mice. Six murine obese mod...

The increasing rate of food waste (FW) generation globally, makes it an attractive resource for renewable energy through anaerobic digestion (AD). biogas recovered from AD can be upgraded by the methanation internally produced carbon dioxide, CO2 with externally sourced hydrogen gas, H2 (biomethanation). In this work, was added to reactors processing FW in three successive phases, digestate pre...

Introduction: Autosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic kidney disorders with the incidence of 1 in 1,000 births. ADPKD is genetically heterogeneous with two genes identified: PKD1 (16p13.3, 46 exons) and PKD2 (4q21, 15 exons). Eighty five percent of the patients with ADPKD have at least one mutation in the PKD1 gene. Genetic studies have demonstrate...

Klebsiella pneumoniae is not only a major hospital-acquired pathogen but also an important food-borne pathogen that can cause septicaemia, liver abscesses, and diarrhea in humans. The phenotypic and genotypic characteristics of K. pneumoniae in retail foods have not been thoroughly investigated in China. The objective of this study was to characterize K. pneumoniae isolates through biotyping, s...

Abstract Aptamers are single-stranded nucleic acids, typically 20-80 nucleobases (nb) in length, which can bind different compounds with high affinity and selectively. Their ligand-binding properties be attenuated by adding short complementary strands. These interactions open new opportunities for aptamer-based assays. Strong dependence between the length electrophoretic mobility of acids makes...

Bone Marrow Growth Supplement is a inexpensive media additive that will greatly improve cell growth and morphology in bone marrows by exposing these cells to growth factors that are known growth promoters. Also effective with difficult to grow solid tumours, lymphomas and products of conception. Advantages that will be seen in bone marrow cultures are the following: a significant improvement in...