Outcomes of three protocols of intensity-modulated radiation therapy (IMRT) for localized prostate cancer were evaluated. A total of 259 patients treated with 5-field IMRT between 2005 and 2011 were analyzed. First, 74 patients were treated with a daily fraction of 2.0 Gy to a total of 74 Gy (low risk) or 78 Gy (intermediate or high risk). Then, 101 patients were treated with a 2.1-Gy daily fra...

PURPOSE/OBJECTIVE(S) IMRT allows dose escalation for large lung tumors, but respiratory motion may compromise delivery. A treatment plan that modulates fluence predominantly in the transversal direction and leaves the fluence identical in the direction of the breathing motion may reduce this problem. MATERIALS/METHODS Planning-CT-datasets of 20 patients with Stage I-IV non small cell lung can...

Radiation is used to sterilize Medflies, Ceratitis capitata (Wied.), for SIT programmes. Massreared flies in the Madeira-Med sterile insect technique (SIT) programme are sterilized at the pupal stage about 24 hours before adult eclosion with 100 Gy using a Gamma Cell 220 loaded with Cobalt 60. The pupae are in anoxia/hypoxia when treated. It is known that the higher the radiation dose given to ...

Cumin is an important spice that has been used for centuries in various cuisines around the world. Two cumin varieties (GC 3 and GC 4) were subjected to mutation understand macromutational modifications. Ethyl methane sulphonate (EMS) @ 0.6% gamma rays (190 Gy) significantly reduced germination plant survival percentage as compared 0.2% EMS 130 Gy. Physical mutagens showed higher suravival than...

The aim of this study was to compare three strategies for intensity-modulated radiotherapy (IMRT) for 20 head-and-neck cancer patients. For simultaneous integrated boost (SIB), doses were 66 and 54 Gy in 30 fractions for PTVboost and PTVelective, respectively. Two-phase IMRT delivered 50 Gy in 25 fractions to PTVelective in the First Plan, and 20 Gy in 10 fractions to PTVboost in the Second Pla...

BACKGROUND It is currently not possible to get an approval of our ethics committee for a randomized trial cmparing 5x4 Gy and 10x3 Gy for MSCC that includes patients with favorable survival prognoses. Therefore, this matched-pair study following strict matching criteria was perfomed instead. METHODS In this study, 142 receiving 5x4 Gy were retrospectively matched (1:1) to 142 patients receivi...

BACKGROUND AND PURPOSE The aim was to demonstrate similar pain relief with two schedules of radiotherapy for painful bone metastases. MATERIALS AND METHODS A total of 160 patients were assigned to receive a single 8-Gy fraction or 30 Gy in 10 fractions. Pain intensity was measured on an ordinal pain scale of 0-10. Partial response was defined as a pain reduction of two points or more and comp...

BACKGROUND AND PURPOSE We report a systematic review of lung radiation doses from breast cancer radiotherapy. METHODS AND MATERIALS Studies describing breast cancer radiotherapy regimens published during 2010-2015 and reporting lung dose were included. Doses were compared between different countries, anatomical regions irradiated, techniques and use of breathing adaptation. RESULTS 471 regi...

To investigate the effects of sanguinarine (SAN) on acute radiation induced injury in mice, 45 mice were randomly divided into control, 10 Gy and SAN+10 Gy groups. Mice in the 10 Gy and SAN+10 Gy groups were exposed to single X-ray radiation with an accumulated dose of 10 Gy. Mice in the SAN+10 Gy group were administered intraperitoneally with 2.5 mg/kg body weight of SAN before radiation. Five...