Context: Suboxone (buprenorphine-naloxone) is an opioid product approved in the US and Canada for treatment of use disorder. The drug considered important response to overdose epidemic with consistent calls wider prescribing deregulation primary care. But there are documented irregularities, or “abuses”, pharmaceutical regulation process that support manufacturer profit-making. Obj...

Importance Since the accidental introduction of yellow-legged hornet (Vespa velutina nigrithorax) in France 2004, there have been reports this insect unexpectedly projecting a liquid toward human face, but ocular morbidity associated with is unknown, to our knowledge. Objective To describe case series lesions after exposure projection emitted by hornet. Design, Sett...

Background Tablet splitting can provide dose flexibility and cost savings; however, pharmaceutical representatives typically discourage the practice. Aim To identify summarise all published concerns related to tablet present experimental evidence that investigates those concerns. Design & setting Systematic review qualitative synthesis of tablet-splitting evidence...

AbstractObjectives Type 2 diabetes is a risk factor for sarcopenia. Evidence on the prevention of sarcopenia using blood glucose–lowering therapy limited. We aimed to examine relationship between changes in glycemic control and effect antidiabetic agents against patients with type diabetes. Design conducted an observational longitudinal study. Setting Participants...

ABSTRACTStudy Objective To characterize typical menstrual characteristics in a large sample of secondary school girls, as well knowledge (ie, normal) menstruation, endometriosis awareness, and educational needs. establish whether self-reported atypical period symptoms indicate suggesting the need for further clinical review specialist opinion. Design Cross-sectional s...

AbstractObjective To examine the mediating effects of food resource management skills (FRM) on relationship between participation in a Supplemental Nutrition Assistance Program Education (SNAP-Ed) nutrition education program and diet quality. Design Secondary analysis data from propensity score-matched sample participants (n = 396) nonparticipants 111) SNAP-Ed ...

Importance Black patients hospitalized with COVID-19 may have worse outcomes than White because of excess individual risk or are disproportionately cared for in hospitals all. Objectives To examine differences hospital mortality rates between and to assess whether the reflect patient characteristics by race which admitted. Design, Setting, Participants This cohort stu...

Background Myocardial fibrosis is an important adverse prognostic marker, however; determinants of myocardial in immune-mediated inflammatory diseases (IMIDs) remain poorly defined. Objectives To identify patients with IMIDs, as measured by cardiovascular magnetic resonance (CMR) extracellular volume (ECV). Methods Cross-sectional study 116 IMIDs undergoing clinical C...

AbstractIntroduction Fibroepithelial polyps (FEP) of the lower urinary tract are relatively common in adults but rare children, with fewer than 250 cases reported literature to date. Objective The aim this study was address experience FEP management children. Study design A retrospective multicenter review undertaken children defined managed between 2008 and ...

AbstractIntroduction Cancer is the second leading cause of death globally. Adverse effects chemotherapy affect physiological and psychological aspects human life. Self-care practice to manage side can improve quality Aims The study investigates relationship between knowledge on adverse self-care ability survivors' effects. Subjects methods This was a single c...