A serological surveillance programme for avian influenza A virus (AIV) subtype H5 and H7 in poultry was implemented in Poland in 2008-2013 with two main objectives: i) to detect subclinical infections or previous exposures to AIV H5 and H7 subtypes and ii) to demonstrate the AI- free status of Poland. During this period, over 45 000 serum samples from 2833 holdings were examined using the hemag...

During translational studies to develop 4-phenyl-2-dimethylaminotetralin (PAT) compounds for neuropsychiatric disorders, the (2R,4S)-trans-(+)- and (2S,4R)-trans-(-)-enantiomers of the analog 6-hydroxy-7-chloro-PAT (6-OH-7-Cl-PAT) demonstrated unusual pharmacology at serotonin (5-HT) 5-HT2 G protein-coupled receptors (GPCRs). The enantiomers had similar affinities (Ki) at human (h) 5-HT2A recep...

The duck histone H5 gene contains a 12 base pair (bp) sequence motif within the coding region, which shows homology in 10 out of 12 bp with the consensus sequence of the USF binding site in the Ad2ML-promoter. The functional equivalent of transcription factor USF, partially purified from whole cell extracts of duck erythrocytes (EUSF), was shown to interact with this intragenic sequence. Electr...

Emergence and intercontinental spread of highly pathogenic avian influenza A(H5Nx) virus clade 2.3.4.4 is unprecedented. H5N8 and H5N2 viruses have caused major economic losses in the poultry industry in Europe and North America, and lethal human infections with H5N6 virus have occurred in Asia. Knowledge of the evolution of receptor-binding specificity of these viruses, which might affect host...

The Ceylon Journal of Science is a peer-reviewed journal published quarterly by the University Peradeniya, Sri Lanka in March, June, September and December. It aimed at publishing high quality research articles on topics related to different disciplines Science. accepts original articles, book reviews, reviews mini-reviews, short communications, opinions, notes, commentaries notes. has its own ...

The Ceylon Journal of Science is a peer-reviewed journal published quarterly by the University Peradeniya, Sri Lanka in March, June, September and December. It aimed at publishing high quality research articles on topics related to different disciplines Science. accepts original articles, book reviews, reviews mini-reviews, short communications, opinions, notes, commentaries notes. has its own ...

The Ceylon Journal of Science is a peer-reviewed journal published quarterly by the University Peradeniya, Sri Lanka in March, June, September and December. It aimed at publishing high quality research articles on topics related to different disciplines Science. accepts original articles, book reviews, reviews mini-reviews, short communications, opinions, notes, commentaries notes. has its own ...

The Ceylon Journal of Science is a peer-reviewed journal published quarterly by the University Peradeniya, Sri Lanka in March, June, September and December. It aimed at publishing high quality research articles on topics related to different disciplines Science. accepts original articles, book reviews, reviews mini-reviews, short communications, opinions, notes, commentaries notes. has its own ...

The Ceylon Journal of Science is a peer-reviewed journal published quarterly by the University Peradeniya, Sri Lanka in March, June, September and December. It aimed at publishing high quality research articles on topics related to different disciplines Science. accepts original articles, book reviews, reviews mini-reviews, short communications, opinions, notes, commentaries notes. has its own ...