Analysis of serum from a patient with cutaneous leukocytoclastic vasculitis showed a mixed cryoglobulin with a monoclonal IgM kappa-antiglobulin component (6.5 mg/ml), strong rheumatoid factor activity (latex titre 1/5000), and positive serological tests for syphilis (fluorescent treponemal antibody-absorbed and Treponema pallidum haemagglutination assay). After removal of antiglobulin activity...

Patients suffering from anorexia nervosa rarely appear to develop the common cold or influenza. This study examines the immunological response of fifteen female anorexia nervosa patients of both the vomiting and carbohydrate-abstaining type and compares them with a control population matched for age and occupation. Both anorectics and control populations received the admune influenza vaccine. I...

Penicillins are B-lactam antibiotics widely used in clinical practice and they induce many allergic reactions, which can be either cellular or humoral. B-lactams are able to interact covalently with serum proteins, forming immunogenic conjugates and their metabolism can provoke a number of different antigenic determinants that have been implicated in the specificity of the immunological respons...

Cold agglutinins (CAs) lead to organ thrombosis or haemolysis due to increased blood viscosity and red blood cell clumping when blood temperature drops below the thermal amplitude for haemagglutination. Although it is well known that CAs are particularly relevant to adult cardiac surgery with hypothermic cardiopulmonary bypass (CPB), paediatric cardiac surgery with congenital heart disease and ...

AIM The aim of the present study was to investigate the immunomodulatory action of methanolic extract of Moringa oleifera (MEMO) in an experimental model of immunity. The cellular immunity was evaluated using neutrophil adhesion test, cyclophosphamide induced neutropenia and carbon clearance assay, whereas, humoral immunity was tested by mice lethality test, serum immunoglobulin estimation and ...

Vaccination is the method of choice for the prevention of influenza infection. However, the quantity of the antigen available, especially in the case of pandemics, often fails to meet the global demand. However, improved adjuvants can overcome this problem. Preliminary results obtained in this study revealed that one year after a single subcutaneous immunisation with influenza A H3N2 virus in a...

A 27 year old woman was admitted to our hospital with a history of a nonproductive cough and breathingdependent chest pain. The symptoms were manifested after a common cold a few weeks earlier. No fever or loss of body weight was noted. The patient’s medical history was remarkable for insulin-dependent diabetes mellitus of 6 yrs duration. She had never smoked. On physical examination, the patie...

The present work was carried out to evaluate different quantitation techniques when Newcastle disease virus was intended to use as an oncolytic agent. The R 2 B Mukteshwar strain of NDV was procured as lyophilized vaccine. Then application were carried out like haemagglutination test, tissue culture infective dose-50 (TCID50), plaque forming unit (PFU) calculation and real time PCR to enumerate...

The emergence of the influenza (H1N1) 2009 virus provided a unique opportunity to study the evolution of a pandemic virus following its introduction into the human population. Virological and clinical surveillance in the UK were comprehensive during the first and second waves of the pandemic in 2009, with extensive laboratory confirmation of infection allowing a detailed sampling of representat...

Paired sera from 60 consecutive patients with acute salpingitis, confirmed by laparoscopy, were examined for serum antibodies to Chlamydia trachomatis, Mycoplasma hominis, and Neisseria gonorrhoeae. By a microimmunofluorescence (MIF) test IgM or IgG antibodies to C trachomatis or both were present in sera from 80% of the patients' by indirect haemagglutination (IHA) tests antibodies to M homini...