The two great advances, which both occurred around 1960, and which presaged the dramatic increase in the understanding of leprosy and its treatment in the following 2 decades, were the development by Ridley and Jopling of their c1assification of leprosy according to immunity, 1 ,2 and the discovery by Shepard of lirnited multiplication of M. leprae in the mouse foot pad.3 The latter was rapidly...

1 Valdes L, Sanjose E, Alvarez D, Sarandeses A, Pose A, Chomon B, et al. Diagnosis of tuberculous pleurisy using the biologic parameters adenosine deaminase, lysozyme, and interferon gamma. Chest 1993; 103:458-65 2 Piras MA, Gakis C, Budroni M, Andreoni C. Adenosine deaminase activity in pleural effusions: an aid to differential diagnosis. Br Med J 1978; ii:1751-52 3 Van Keimpema AR, Slaats EH,...

the script and orthography system which are used for the zoroastrian middle persian (= pahlavi) texts because of their many shortcomings and difficulties have always caused many misunderstandings and misinterpretations by the ancient users and modern researchers. this indeterminacy of the script and the lack of a complete and accurate understanding of the contents of the texts have caused the p...

Cohen AD, Price JC, Weissfeld LA, James J, Rosario BL, Bi W, et al. Basal cerebral metabolism may modulate the cognitive effects of Abeta in mild cognitive impairment: an example of brain reserve. J Neurosci 2009; 29: 14770–8. Doody RS, Thomas RG, Farlow M, Iwatsubo T, Vellas B, Joffe S, et al. Phase 3 trials of solanezumab for mild-tomoderate Alzheimer’s disease. N Engl J Med 2014; 370: 311–21...

The kinetics of the membrane current during the anomalous or inward-going rectification of the K current in the egg cell membrane of the starfish Mediaster aequalis were analyzed by voltage clamp. The rectification has instantaneous and time-dependent components. The time-dependent increase in the K conductance for the negative voltage pulse as well as the decrease in the conductance for the po...

1. Lukinmaa S, Nakari UM, Liimatainen A, Siitonen A. Genomic diversity within phage types of Salmonella enterica ssp. enterica serotypes Enteritidis and Typhimurium. Foodborne Pathog Dis. 2006;3:97–105. http://dx.doi.org/10.1089/fpd.2006.3.97 2. Soyer Y, Moreno Switt A, Davis MA, Maurer J, McDonough PL, Schoonmaker-Bopp DJ, et al. Salmonella enterica serotype 4,5,12:I:-, an emerging Salmonella ...

Geometric characteristics of 2-manifolds embedded in R space have been analyzed from the point of view of differential geometry and topology. In the past, results relevant to these areas have been found for C curves and surfaces. However, current scientific, industrial, entertainment and medical applications, and availability of more powerful point sampling systems, press for characterization o...