The objective was to compare different procedures for determination of haptoglobin in bovine plasma. Nine Angus steers were vaccinated against Mannheimia haemolytica to stimulate an acute-phase response. Blood samples were collected immediately prior to vaccination (day 0), and on days 1, 3, 5, 7 and 10. Plasma samples were frozen in duplicates at -80 °C. One set of the duplicates was analysed ...

BACKGROUND Haptoglobin acts as an antioxidant by limiting peroxidative tissue damage by free hemoglobin. The haptoglobin gene allele Hp2 comprises a 1.7 kb partial duplication. Relative to allele Hp1, Hp2 carriers form protein multimers, suboptimal for hemoglobin scavenging. OBJECTIVE To examine the association of haptoglobin genotype with a range of phenotypes, with emphasis on vitamin C and...

Assuming that haptoglobin, by virtue of its immunomodulatory properties, could be a regulatory factor during reproduction, its presence in the human uterus was determined. Protein extracts from endometrial tissue samples of pregnant and non-pregnant women were analysed by the immunoblot technique and the intensities of specific bands were quantified. Bands corresponding to haptoglobin were iden...

Human hemoglobin (aNOD), in which a! chains were liganded with nitric oxide and p chains were unliganded, showed a characteristic spectrum in the Soret region. Its absorption was significantly reduced compared with the averaged absorption of IX-NO and p. On the other hand, a complex of (cuNO0) with haptoglobin did not show such a characteristic spectrum. It was concluded, therefore, that there ...

BACKGROUND There is a marked difference in the degree of expression of the homozygous C282Y HFE genotype that is associated with hereditary hemochromatosis. It has been reported that individuals with the haptoglobin 2-2 type manifest increased iron concentrations, including serum iron, transferrin saturation, and ferritin. METHODS We studied 232 patients, 115 homozygous for the c.845G-->A (C2...

adnexal tumors (ats) are primary skin tumors with benign or rarely, malignant behavior. they have been classified based on differentiation towards hair follicle, sebaceous, apocrine or eccrine gland. few large-scale studies have focused on ats. to determine the prevalence of ats and to assess clinical and histopathological trend of ats. a retrospective descriptive study of all ats diagnosed in ...

OBJECTIVE Haptoglobin is a plasma protein that binds free hemoglobin, thereby inhibiting hemoglobin-induced oxidative damage. We investigated the association between the haptoglobin genotype and the incidence of coronary artery disease (CAD) in a cohort of individuals with childhood-onset type 1 diabetes. RESEARCH DESIGN AND METHODS Participants from the Epidemiology of Diabetes Complications...

the objective of this study was to evaluate the concentration of these acute phase proteins(serum amyloid a, milk amyloid a and serum haptoglobin) and alteration in hematological values in some inflammatory diseases in dairy cattle. fifty-six holstein dairy cows with some inflammatory diseases were used in this study including: subclinical mastitis, hematological infections (theileriosis and an...

Haptoglobin phenotypes have been determined in 30 chronic lymphatic leukaemia patients and concentrations determined in 21 of these. The number ofHpl phenotypes is slightly raised but not significantly so compared with a control population and is the same as that in first-degree relatives. Haptoglobin concentrations show higher concentrations in Hpl than Hp2, as has previously been reported. It...