نتایج جستجو برای: harmine
تعداد نتایج: 271 فیلتر نتایج به سال:
The DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) gene encodes a proline-directed Ser/Thr kinase. Elevated expression and/or altered distribution of the kinase have been implicated in the neurological impairments associated with Down syndrome (DS) and Alzheimer’s disease (AD). Consequently, DYRK1A inhibition has been of significant interest as a potential strategy for t...
The DYRK1A (dual specificity tyrosine phosphorylation-regulated kinase 1A) gene encodes a proline-directed Ser/Thr kinase. Elevated expression and/or altered distribution of the kinase have been implicated in the neurological impairments associated with Down syndrome (DS) and Alzheimer’s disease (AD). Consequently, DYRK1A inhibition has been of significant interest as a potential strategy for t...
Background: -Carboline alkaloids are normal body constituents but are also potent tremor-producing chemicals that are naturally present in the food chain. Objective: To explore the hypothesis that high concentrations of -carboline alkaloids are associated with essential tremor (ET). Methods: One hundred cases and 100 controls were frequency matched on age, sex, and ethnicity. Blood concentratio...
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