BACKGROUND Occult hepatitis B infection (OBI) is characterized by negative hepatitis B surface antigen (HBsAg) and detectable hepatitis B virus (HBV)-DNA in the liver and/or serum, with or without hepatitis B core antibody (anti-HBc). Anti-HBc is the most sensitive marker of previous HBV. HBV reactivation in patients under immunosuppressive treatment is life-threatening, occurring in both overt...

background: the outcome of hepatitis b virus (hbv) infection is chronic or resolved hbv infection. over the time, the levels of hbsag or anti-hbs declined and were not detectable in their sera and was named as isolated anti-hbc. the purpose of this study was to assess the prevalence of isolated anti-hbc in previously hbv infected individuals.methods: from april 2000 to september 2008, the resul...

Human body communication (HBC) is a promising wireless technology that uses the human body as part of the communication channel. HBC operates in the near-field of the high frequency (HF) band and in the lower frequencies of the very high frequency (VHF) band, where the electromagnetic field has the tendency to be confined inside the human body. Electromagnetic interference poses a serious relia...

  Background and Objective: Presence of hepatitis B core antibody (anti-HBc) in the absence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) is defined, as isolated anti-HBc. little is known about the clinical significance of the isolated anti-HBc in hepatitis B virus (HBV) infections. The aim of this study was to assess the significance of anti-HBc as the onl...

Background: The outcome of Hepatitis B virus (HBV) infection is chronic or resolved HBV infection. Over the time, the levels of HBsAg or Anti-HBs declined and were not detectable in their sera and was named as isolated anti-HBc. The purpose of this study was to assess the prevalence of isolated anti-HBc in previously HBV infected individuals.Methods: From April 2000 to September 2008, the resul...

Objective: During viral hepatitis B, serum HBsAg and HBeAg were important indexes reflecting viral replication and liver inflammation. However, patients with negative serum HBeAg still developed viremia or inflammatory necrosis. Negative HBsAg patients also had serum HBV DNA. This study thus analysed patients who were negative for HABsAg or HBeAg, to provide evidences for diagnosing chronic hep...

Circulating microRNAs (miRNAs) can be employed as biomarkers to diagnose liver and other diseases. Noninvasive approaches are needed to complement and improve the current strategies for screening for biomarkers liver cirrhosis. We determined whether the serum levels of miRNAs can distinguish between chronic hepatitis B (CHB) and CHB-induced cirrhosis (HBC) and investigated the potential mechani...

Diagnosis of hepatitis B is routinely based on of serological assay of hepatitis B surface antigen (HBsAg). Occult hepatitis B virus (HBV) infection is generally defined as the detection of HBV -DNA in the serum or tissues of subjects who have negative test for HBsAg. Transmission of HBV infection has been documented from HBsAg negative, anti-HBc positive blood and organ donors. The aim of this...

The clinical significance of isolated anti-HBc is still a challenge. To elucidate the real importance of this finding in our blood donors, an investigation algorithm was tested. One hundred and twelve isolated anti-HBc seropositive blood donors underwent clinical evaluation and retesting of HBV markers. Those who presented repeatedly reactive isolated anti-HBc, received a single dose of hepatit...