Until now, clinicians have been relying solely on LH activity-dependent triggering of final oocyte maturation and thus taken it for granted that the natural midcycle FSH surge is biologically redundant. However, it is time to question this paradigm. Evidence from clinical studies hint that in a yet-to-be-defined subset of patients, dual LH and FSH surge is advantageous compared with LH-only sur...

Abstract Study question Is patients’ BMI associated with oocyte yield and maturation following different trigger strategies r-hCG, GnRH agonist (GnRHa) or dual trigger? Summary answer Patients’ is not triggering rhCG, GnRHa trigger. What known already Triggering final a key step of ovarian stimulation for IVF/ICSI treatment. Although hCG has traditionally been the gold standard maturation, incr...

Objective: Aim of this study was to identify the necessity of use of exogenous or surrogate LH for triggering of ovulation in induced cycles. Materials and methods: This study was conducted in Infertility Care and Research Center (ICRC) Dhaka, Bangladesh. Three hundred anovulatory patients with polycystic ovarian syndrome (PCOS) were the target population for this study. The patients were treat...

background: human chorionic gonadotropin (hcg) has been used as a replacement for the mid-cycle luteinizing hormone (lh) surge for several years. the recent arrival of recombinant dna technology has made recombinant hcg (rhcg) accessible. objective: to assess efficacy of rhcg compared to urinary hcg (uhcg) for triggering of ovulation and induction of final oocyte maturation in assisted reproduc...

BACKGROUND Human chorionic gonadotropin (HCG) has been used as a replacement for the mid-cycle luteinizing hormone (LH) surge for several years. The recent arrival of recombinant DNA technology has made recombinant HCG (rHCG) accessible. OBJECTIVE To assess efficacy of rHCG compared to urinary HCG (uHCG) for triggering of ovulation and induction of final oocyte maturation in assisted reproduc...

Sir, We would like to thank Dr Manno for the comments regarding pre-ovulatory progesterone levels in our paper on controlled ovarian stimulation with hCG supplementation (Thuesen et al., 2012). Dr Manno concluded that our study was another study denying a prognostic value to pre-triggering P4 levels. We think that our study should not be used to clarify a possible role of elevated progesterone ...

Recently, several new promising modifications have been introduced to clinical practice that may simplify and optimize IVF outcome. In the present opinion paper we present a simplified approach to controlled ovarian hyperstimulation protocol (COH), which combines the benefits of the ultrashort flare GnRH agonist/GnRH antagonist protocol and the personalized tailored mode and timing of ovulation...