with an estimated 170 million infected individuals, hepatitis c virus (hcv) has a major impact on public health. frequency of hcv infection was studied in 785 referred patients to a private laboratory, tehran, iran from april 2003 until march 2006 by pcr method. analyzed results revealed infection rate was 40.27%, 35.51% and 33.09% in the first, second and third year, respectively. frequency ra...

Abstract Background HCV and HIV co-infected patients develop cirrhosis more rapidly than mono-infection. Intestinal injury microbial translocation are postulated mechanisms for the rapid progression of cirrhosis. Aim Study effect treatment with DAAs on serum intestinal fatty acid binding protein (I-FABP) as a marker in HCV/HIV its relation to hepatic fibrosis. Comparing level I-FABP mono-infect...

Abstract Globally, approximately 1.5 million new Hepatitis C virus (HCV) infections occur annually. A vaccine to prevent chronic HCV infection would limit transmission and pathogenesis of HCV. To understand immunity in high risk populations, we prospectively followed antibody negative high-risk people who inject drugs (PWIDs) a protocol designed for monthly follow-up. We demonstrated previously...

Background and Aims: Hepatitis C is a blood-borne virus that causes a liver inflammation. The prevalence of hepatitis C (HCV) in hemodialysis patients is more than the general population. Periodic screening of HCV in dialysis centers is necessary to control this viral disease.  The aim of this study is the evaluation of HCV infection among hemodialysis patients living in Yazd province of...

With the development of science and technology, amazing function gut microbiota is being understood more each day. A person's physiological, metabolic, even mental health are all touched by a tiny imbalance in intestinal microbial community. It has been suggested that such microbiome dysbiosis contributes to variety infections, including bacterial, fungal, parasitic, viral infections. Throughou...