Squamous cell carcinoma of the neck presenting clinically as predominantly cystic lesion has often been considered as branchiogenic carcinoma in the past. However, such cystic lesions presently constitute a distinct form of head-neck metastasis, and a co-existent second metastatic focus could supposedly help distinguish them from branchiogenic carcinoma. We here present a case where, although t...

Squamous cell carcinoma is the most common head and neck cancer. This review describes the state-of-the-art computerised tomography and magnetic resonance imaging protocols of the neck and the normal larynx anatomy, and provides a practical approach for the diagnosis and staging of laryngeal squamous cell carcinoma.

OBJECTIVE To determine if prodrug conversion of fluorocytosine to fluorouracil by an engineered herpes virus, OncoVEX(GALV/CD), enhances oncolytic therapy of head and neck squamous cell carcinoma. DESIGN We assessed the ability of OncoVEX(GALV/CD) and OncoVEX(GFP) to infect, replicate within, and lyse 4 head and neck squamous cell carcinoma lines in vitro. The effects of adding fluorocytosine...

Mouse models can closely mimic human oral squamous epithelial carcinogenesis, greatly expand the in vivo research possibilities, and play a critical role in the development of diagnosis, monitoring, and treatment of head and neck squamous cell carcinoma. With the development of the recent research on the contribution of immunity/inflammation to cancer initiation and progression, mouse models ha...

Oral cavity squamous cell carcinoma is one of the leading localizations in structure head and neck cancers Russian federation world. Neck metastases are key criterion which influence to survival, recurrence, distant patients with oral carcinoma. dissection a main step surgical treatment This literature review analyzes data on possible methods for assessing quality cavity. Evaluation criteria ca...

Cisplatin plus fluorouracil (5-FU) is widely accepted as neoadjuvant and adjuvant chemotherapy in the treatment of head and neck squamous cell carcinoma; UFT is also an active agent against this disease. In the first retrospective study, we examined the efficacy of UFT as adjuvant chemotherapy in patients with maxillary cancer. The 5-year survival rate of those treated with UFT vs those not tre...

Radiotherapy plays an important role in the treatment of most solid tumors including head and neck squamous cell carcinoma (HNSCC). Radioresistance can lead to locoregional recurrence distant metastases. Despite significant progress research radioresistance, its prediction overcoming strategies remain challenging. This review describes potential biomarkers correlated radioresistance complex sig...

Cutaneous squamous cell carcinoma of the head and neck is an invasive skin cancer with significant morbidity and mortality, chiefly among older and immunocompromised patients. We present a case report of a patient without obvious immune suppression developing multiple, eruptive cutaneous squamous cell carcinomas of the scalp. Despite multiple excisions, radiotherapy and adjuvant oral retinoids,...

PURPOSE Human cell lines are useful for studying cancer biology and preclinically modeling cancer therapy, but can be misidentified and cross-contamination is unfortunately common. The purpose of this study was to develop a panel of validated head and neck cell lines representing the spectrum of tissue sites and histologies that could be used for studying the molecular, genetic, and phenotypic ...

Orofacial squamous cell carcinoma (OfSCC) accounts for up to 90% of all malignant lesions in the head and neck region. This study aimed document histopathological characteristics OfSCC a Tanzanian population concerning age presentation, gender, site occurrence. was retrospective carried out at department Oral Maxillofacial Surgery, Muhimbili National Hospital. It included histological results d...