Robots are rapidly advancing toward becoming autonomous and skilled entities in a wide range of environments, and it is likely that more and more people will soon be interacting with robots in their everyday lives. As this happens, we believe that it is crucial that robots are designed to be easy to use and understand, reducing the requirement for people and environments to adapt to the robot. ...

The heme-regulated inhibitor (HRI), a member of the eIF-2α kinase family is crucial for regulating protein synthesis during stress. In addition to heme, stress proteins Hsp90 and Hsp70 are known to regulate HRI. The present study aims to determine the physical association of these Hsps in the regulation of HRI activation during oxidative stress using human K562 cells as a model. Extracts from t...

Heme-regulated eIF2α kinase (HRI) controls protein synthesis by phosphorylating the α-subunit of eukaryotic translational initiation factor 2 (eIF2α). In heme deficiency, HRI is essential for translational regulation of αand β-globins and for the survival of erythroid progenitors. HRI is also activated by a number of cytoplasmic stresses other than heme deficiency, including oxidative stress an...

Abstract Background and aim Currently, nonalcoholic liver disease (NAFLD) is the most predominant chronic disorder. NAFLD has been linked to hepatic extrahepatic morbidities. We aimed investigate role of acoustic radiation force impulse (ARFI), hepatorenal index (HRI), serum microRNA-130b as non-invasive predictors for kidney (CKD) in patients. Material methods In a case–control design, we incl...

The heme-regulated inhibitor (HRI) negatively regulates protein synthesis by phosphorylating eukaryotic initiation factor-2alpha (eIF2alpha) thereby inhibiting protein translation. The importance of HRI in regulating hemoglobin synthesis in erythroid cells makes it an attractive molecular target in need of further characterization. In this work, we have cloned and expressed the canine form of t...

This paper describes our approach for human-robot interaction (HRI) research and summarizes our progress to date. We have concentrated on HRI in urban search and rescue (USAR) because it is an example of a safety-critical application. We analyzed the performance of robotic teams at two USAR robotics competitions using adaptations of techniques from the human-computer interaction (HCI) field and...

During erythroid differentiation and maturation, it is critical that the 3 components of hemoglobin, alpha-globin, beta-globin, and heme, are made in proper stoichiometry to form stable hemoglobin. Heme-regulated translation mediated by the heme-regulated inhibitor kinase (HRI) provides one major mechanism that ensures balanced synthesis of globins and heme. HRI phosphorylates the alpha-subunit...

This document is divided into two parts. The first part details the authors opinion on the three questions posed by the ICRA NEWHRI 2008 workshop. The second part represents a brief introduction to the research conducted by the author toward realization of autonomous robots that can learn interactive behavior through real world interactions with humans. I. CHARACTERIZING HRI A. What characteris...

OBJECTIVES Underweight, overweight, and obese women aged 18-34 years were compared with normal weight women of the corresponding age according to socioeconomic, psychosocial, health behaviour, self reported global and psychological health, and locus of control characteristics. METHODS The 2000 public health survey in Scania is a cross-sectional study. A total 13,715 persons aged 18-80 years, ...

Abstract This contribution to the journal Gruppe. Interaktion. Organisation. (GIO) presents a checklist of questions and design recommendations for designing acceptable trustworthy human-robot interaction (HRI). In order extend application scope robots towards more complex contexts in public domain private households, have fulfill requirements regarding social between humans addition safety eff...