Photodynamic therapy (PDT) is a promising non-invasive therapeutic modality that has been proposed for treating prostate cancer, but the procedure is associated with limited efficacy, tumor recurrence and photo-toxicity. In the present study, we proposed to develop a novel multifunctional nano-platform for targeted delivery of heat, reactive oxygen species (ROS) and heat shock protein 90 (Hsp90...

STUDY DESIGNBlinded randomized controlled trial.INTRODUCTIONIt is generally accepted that heat is beneficial for improving range of motion (ROM). However, the mechanism of action is not clearly understood, and the optimal method of heat application has not been established.PURPOSE OF THE STUDYTo investigate the immediate effects of using a moist hot pack (MHP) vs therapeutic whirlpool bath (WB)...

Multimodal oncological strategies which combine chemotherapy or radiotherapy with hyperthermia, have a potential of improving the efficacy of the non-surgical methods of cancer treatment. Hyperthermia engages the heat-shock response (HSR) mechanism, the main component of which are heat-shock proteins. Cancer cells have already partially activated HSR, thereby hyperthermia may be more toxic to t...

Introduction: The photo-thermal therapy by nanoparticles has been recently known as an efficient strategy for the cancer treatment. Carbon nanotubes (CNTs) have been extensively studied in biomedical application due to the easy uptake and high permeability in the cells, biocompatibility in biological environments and also their unique electrical, thermal properties. They genera...

The primary determinant of vascular adaptations to lifestyle interventions, such as exercise and heat therapy, is repeated elevations in shear stress. Whether skin or core temperatures also modulate the adaptation acute exposure unknown, likely due difficulty dissociating thermal hemodynamic responses heat. We found that modify passive heating irrespective magnitude increase

background: labor pain is one of the severest pains that cause many women request cesarean section for fear of pain. thus, controlling labor pain is a major concern of maternity care. nowadays, interest in non-pharmacological pain relief methods has been increased because of their lower side effects. the effects of discrete heat and cold on decreasing labor pain have been reported but there was...

BACKGROUND Heat is commonly used in physical therapy following exercise induced delayed onset muscle soreness (DOMS). Most heat modalities used in a clinical setting for DOMS are only applied for 5 to 20 minutes. This minimal heat exposure causes little, if any, change in deep tissue temperature. For this reason, long duration dry chemical heat packs are used at home to slowly and safely warm t...

background: although there is convincing data in support of the effectiveness of hyperthermia in tumor therapy, the molecular mechanisms underlying the clinical effects of hyperthermia are still poorly understood. objective: to investigate natural killer (nk) cell cytotoxicity against heat-treated sw-872 and hela tumor cell lines. methods: nkg2d ligands and hla class i transcription were examin...

Infants and children are at higher risk of heat stroke for several reasons. We report these cases to highlight the danger of leaving children unsupervised in vehicles, aid prompt diagnosis, and management of heat stroke. Two Nigerian siblings aged ranges 5 and 3 years old, were trapped inside an unlocked vehicle and subsequently developed heat stroke. Both children presented with hyperthermia, ...

of supportive care and emergency medicine is necessary for the successful medical management of avian patients. The basic concepts of emergency and supportive care of small animal medicine apply to birds, but modifications must be made to compensate for their unique anatomy and physiology. Supportive care including fluid therapy, nutritional support, and heat and oxygen supplementation is criti...