altered glycosylation of proteins in cancer cells is one of the main processes responsible for anaplasia, invasion and metastatic potential of neoplastic cells. lectins are nonimmunogenetic compounds which specifically detect certain terminal sugars of glycoconjugates. the aim of the present study was to identify the n-acetylgalactosamine (galnac) containing glycoconjugates in cancer cells in a...

In this work, we deal with a classical differential geometry topic in Minkowski space-time. First, we prove that there are no timelike involutes of a time-like evolute. In the light of this result, we observed that involute curve transforms to a time-like curve when evolute is a space-like helix with a time-like principal normal. Then, we investigated relationships among Frenet-Serret apparatus...

The polyproline helix type II (PPII) is a regular protein secondary structure with remarkable features. Many studies have highlighted different crucial biological roles supported by this local conformation, e.g. in the interactions between biological macromolecules. Although PPII is less frequently present than regular secondary structures such as canonical alpha helices and beta strands, it co...

Inclined curves or so-called general helices are well-known curves in the classical differential geometry of space curves [9] and we refer to the reader for recent works on this type of curves [6, 12]. Recently, Izumiya and Takeuchi have introduced the concept of slant helix in Euclidean 3-space E saying that the normal lines makes a constant angle with a fixed direction [7]. They characterize ...

Helical piles are foundation systems used to support compression, tension, and lateral loads. However, this type of was around the world for more than 25 years. Its behavior, especially in Iraq, is still unknown scare. The present study carried out by analyses pile using finite element method. Modeling helical geometry has been proposed through computer program Plaxis 3D. Parametric were also p...

While much is known about different allosteric regulation mechanisms, the nature of signal and time scale on which it propagates remains elusive. The PDZ3 domain from postsynaptic density-95 protein a small with terminal third ?-helix, i.e., ?3-helix, to be allosterically active. By cross-linking helix an azobenzene moiety, we obtained photocontrollable variant. Photoswitching triggers its tran...