BACKGROUND The hemoglobinopathies refer to a diverse group of inherited disorders characterized by a reduced synthesis of one or more globin chains (thalassemias) or the synthesis of structurally abnormal hemoglobin (Hb). The thalassemias often coexist with a variety of structural Hb variants giving rise to complex genotypes and an extremely wide spectrum of clinical and hematological phenotype...

Background: Hemoglobinopathies constitute the commonest recessive monogenic disorders worldwide, and treatment of affected individuals presents a substantial global disease burden. Objectives: The purpose this study is to assess quality life among adolescents with hemoglobinopathies in Karbala City/ Iraq. Methods: cross-sectional quantitative approach was carried out on 200 participants who wer...

High-performance liquid chromatography is a technic that has recently been applied to the diagnosis of hemoglobinopathies and thalassemias. Its advantages over other methods include increased sensitivity, resolution and simplicity, as well as speed. In this report, the authors present an HPLC procedure that uses a weak cation exchange column and a gradient elution system for the diagnosis of he...