BACKGROUND Subcapsular hepatic steatosis is a rare atypical pattern of fatty deposition of the liver reported in patients with diabetic nephropathy receiving peritoneal dialysis with intraperitoneal insulin. To date, there has been only one pediatric and zero adult cases of subcapsular hepatic steatosis with no history of continuous ambulatory peritoneal dialysis. We report the first published ...

BACKGROUND Hepatic steatosis renders hepatocytes vulnerable to injury, resulting in the progression of preexisting liver disease. Previous animal and cell culture studies implicated mammalian target of rapamycin (mTOR), signal transducer and activator of transcription-3 (STAT3), extracellular signal-regulated kinase (ERK) and estrogen-receptor α in the pathogenesis of hepatic steatosis and dise...

OBJECTIVE To review present knowledge of the influence of hepatic steatosis in liver surgery as derived from experimental and clinical studies. SUMMARY BACKGROUND DATA Hepatic steatosis is the most common chronic liver disease in the Western world, and it is associated with obesity, diabetes, and metabolic syndrome. Fatty accumulation affects hepatocyte homeostasis and potentially impairs rec...

Abstract Introduction. Hepatic steatosis represents a common pathological feature in patients with chronic viral C infection and can be independently associated obesity, increased alcohol consumption, type 2 diabetes, hyperlipidemia. These factors contribute to the development of hepatic HCV (Hepatitis virus) infection. Materials methods. 64 who underwent treatment oral antivirals were included...

Aim: The aim of the study is to investigate whether there a correlation between severity pneumonia and fatty liver disease in COVID-19. Material Method: In this chest computed tomography (CT) images 168 patients who were confirmed be COVID-19 positive according nasopharyngeal swab specimens evaluated. presence hepatic steatosis evaluated on CT images.Results: aged 26 89, mean age was 63.6 ± 12....

Ultrasound B-mode imaging based on log-compressed envelope data has been widely applied to examine hepatic steatosis. Modeling raw backscattered signals returned from the liver parenchyma by using statistical distributions can provide additional information to assist in hepatic steatosis diagnosis. Since raw data are not always available in modern ultrasound systems, information entropy, which ...

BACKGROUND Genetic variation near the interferon lambda 3 (IFNL3) is known to be associated with response to pegylated interferon (pegIFN) and ribavirin combination therapy in patients with chronic hepatitis C virus (HCV) infection which is often accompanied by hepatic steatosis. AIMS We examined whether this genetic variation is associated with host lipids and treatment response. METHODS A...

Hepatic fatty acid (FA) composition may influence steatosis development in patients with chronic hepatitis C (CHC). In a cross-sectional study, we compared the hepatic FA profile in hepatitis C patients with (n = 9) and without (n = 33) steatosis (> or =5% of hepatocytes involved). FA composition of hepatic and RBC total lipids was measured by gas chromatography. Lipid peroxidation and antioxid...

The influence of patatin-like phospholipase domain-containing 3 (PNPLA3) genetic variants in the development of liver steatosis in Asian chronic hepatitis C patients remains elusive. A total of 1018 biopsy-proven chronic hepatitis C patients were enrolled for evaluation. The proportions of PNPLA3 rs738409 GG genotype carriage were 7.8% (44/563), 15.8% (58/367) and 19.3% (17/88) in patients with...

Hepatitis C virus (HCV) infects 130-170 million people worldwide. Recently, direct-acting antivirals have been shown to eradicate HCV infection in 90-95 % of non-cirrhotic patients depending on genotype, treatment experience, and regimen used. Similar rates are achieved among compensated cirrhotics, although longer treatment duration and/or ribavirin may be required. HCV uses host lipid metabol...