Background and Objective: Presence of hepatitis B core antibody (anti-HBc) in the absence of hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) is defined, as isolated anti-HBc. little is known about the clinical significance of the isolated anti-HBc in hepatitis B virus (HBV) infections. The aim of this study was to assess the significance of anti-HBc as the onl...

hepatitis b virus (hbv) dna polymerase transactivated protein 1 (hbvdnaptp1) is a novel protein transactivated by hbv dna polymerase, screened by suppression subtractive hybridization technique (genbank accession no: ay450389). the biological function of hbvdnaptp1 was investigated in this study.we constructed a vector pcdna3.1 (-)/myc-his a-hbvdnaptp1 and used it to transfect acute monocytic l...

Hepatitis B surface antigen, DNA polymerase, and hepatitis B virus DNA have been sought in the tears of 72 patients. These markers were detected in a high percentage of hepatitis B carriers, which proves the presence of hepatitis B virus in the tears and raises the question of its eventual transmission in this way. The severity and extreme contagiousness of hepatitis B together with the increas...

background: serial measurement of  hepatitis b virus (hbv) dna levels in the liver and its relation with liver damage and serum hbv dna levels are guide to begin and/or end a treatment course. this study evaluated the relationship between liver hepatitis b dna viral load with liver histology in patients with chronic hepatitis b (hbv). methods:  thirty patients with chronic anti-hbe positive hep...

This study assessed the seroepidemiology of Toxoplasma gondii, Hepatitis B Virus and their co-infection infection in women of child-bearing age in communities in Osun State, Nigeria. The study also determines the factors that facilitate the organisms among the studied groups and possible interaction between the prevalence of infection and the risk factors. These were done with a view to providi...

background: sen virus (senv) is the latest virus proposed as a cause of unknown hepatitis cases. among nine detected genotypes of the virus, genotypes d and h are more frequent in hepatitis cases of unknown origin. the aim of this study was to determine the frequency of senv-d and senv-h genotypes in the sera of healthy individuals and hepatitis b and c patients. methods: totally, 200 serum sam...

In patients undergoing chemotherapy for the treatment of malignant disease, the reactivation of hepatitis B virus in hepatitis B surface antigen-positive patients has been frequently reported. However, activation has also been reported in hepatitis B surface antigen-negative patients who test positive for hepatitis B core antibody and/or hepatitis B surface antibody, who were thought to have ha...

background oxidative stress plays a major pathogenic role in liver injury following chronic hepatitis b. glutathione peroxidase (gpx) has a central role in regulating the oxidative state. hepatitis b virus (hbv) results in down-regulation of gpx. on the other hand, iron homeostasis is disrupted in hbv infected patients. therefore, the objective of this study was to assess the interplay of gpx a...