Could infections really have something to do with disorders that cause dementia? Several chronic diseases, such as peptic ulcer, certain cancers, and autoimmune conditions, have established infectious etiologies, either bacterial or viral, but mainstream cognitive disorder research has not fully considered microbial involvement. Evidence is emerging, but the size of the problem— millions of pat...

Introduction The herpes zoster oticus results from the reactivation of varicella virus, a DNA virus Herpesviridae family with strictly human-to-human contamination, affecting geniculate ganglion facial nerve. manifestations shingles and post-herpes signs are associated psychiatric such as anxiety, insomnia depressive disorder. Shingles disorder share common features, decreased cellular immunity...

Latency within the nervous system is a characteristic feature of herpesviridae infection. It is reactivated by triggering factors such as UV exposure, stress, and trauma. Simultaneous reactivation of herpes simplex and herpes zoster is uncommon, however, an observation provably explained by differences in the triggering mechanism. Concurrent reactivation of herpes simplex virus (HSV) and varice...

background the etiology of the guillain-barre syndrome (gbs) is not clear; in many cases, gbs is triggered by a bacterial or viral illness. objectives to evaluate the role of active infection with herpesviridae group and its association with this syndrome we have investigated the cerebrospinal fluid (csf) and serum of patients with gbs for detection of these viruses. patients and methods in a pr...

Herpes simplex virus (HSV)--and herpesviruses in general--encode for a multipartite entry/fusion apparatus. In HSV it consists of the HSV-specific glycoprotein D (gD), and three additional glycoproteins, gH/gL and gB, conserved across the Herpesviridae family and responsible for the execution of fusion. According to the current model, upon receptor binding, gD propagates the activation to gH/gL...