purposes is a demanding task, especially to find recognition parameters for some consonants. In this paper, we show the initial analysis results of speech corpus, sampled with two sampling rates, 22050 and 8000 Hz, using Higuchi fractal dimension. The study shows that it might be possible to use fractal dimension value for classification of for example plosives /k/, /p/ and /t/. However, the an...

* contact author Human Genome Center, Institute of Medical Science, University of Tokyo 4-6-1 Shirokanedai, Minato-ku, Tokyo, 108-8639, Japan {imoto, takao, miyano}@ims.u-tokyo.ac.jp The Institute of Statistical Mathematics, 4-6-7, Minami-Azabu, Minato-ku, Tokyo, 106-8569, Japan [email protected] Graduate School of Genetic Resources Technology, Kyushu University 6-10-1 Hakozaki, Higashi-ku, Fuk...

Kumpei Tanisawa, Tomoko Ito, Xiaomin Sun, Ryuken Ise, Satomi Oshima, Zhen-Bo Cao, Shizuo Sakamoto, Masashi Tanaka, and Mitsuru Higuchi Graduate School of Sport Sciences, Waseda University, Tokorozawa, Saitama, Japan; Department of Genomics for Longevity and Health, Tokyo Metropolitan Institute of Gerontology, Itabashi, Tokyo, Japan; Faculty of Sport Sciences, Waseda University, Tokorozawa, Sait...

There is a well known result from the Fierz-Pauli (FP) theory in de Sitter background that existence of lower bound for mass $m$ spin 2 particle, Higuchi bound. It establishes $m^2\geq 2H^2$, where $H$ Hubble parameter, order to presents no ghost-like instabilities. In this sense, should be unacceptable high fulfill condition at time inflationary epoch Universe, posing difficulty conciliate FP ...

A sustained-release tablet formulation should ideally have a proper release profile insensitive to moderate changes in tablet hardness that is usually encountered in manufacturing. In this study, matrix aspirin (acetylsalicylic acid) tablets with ethylcellulose (EC), Eudragit RS100 (RS), and Eudragit S100 (S) were prepared by direct compression. The release behaviors were then studied in two co...

Release properties from a wax matrix tablet was examined. To obtain basic release properties, the wax matrix tablet was prepared from a physical mixture of drug and wax powder (hydrogenated caster oil) at a fixed mixing ratio. Properties of release from the single flat-faced surface or curved side surface of the wax matrix tablet were examined. The applicability of the square-root time law and ...

The influence of excipients on the disintegration times of tablets and the release of papaverine hydrochloride (PAP) from tablets were studied. Ten different formulations of tablets with PAP were prepared by direct powder compression. Different binders, disintegrants, fillers, and lubricants were used as excipients. The release of PAP was carried out in the paddle apparatus using 0.1 N HCl as a...

Objective: The objective of the present work was to formulate a gastroretentive dosage form of Valacyclovir, an anti viral drug. Methods: Valacyclovir gastroretentive mucoadhesive tablets were prepared using polymers such as Carbopol 974P and hydroxy propyl methyl cellulose (HPMC) K4M, in different proportions by wet granulation technique. Compatibility studies were performed by FTIR spectrosco...

The aim of this work was to investigate the effect of ethanol on the in vitro swelling and release behaviors of Carbopol(®)-based tablets. The swelling behavior of drug-free compacts and the release of model drugs (metformin HCl, caffeine and theophylline) from matrix tablets were evaluated in acidic and buffered media with 0, 20 and 40% (v/v) ethanol. Release data were analyzed by fitting to H...