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The aim of this study was to determine the role surgical stress on formation p53-positive and dark neurons (DN) in hippocampus, examine parallelism their pyramidal layer hippocampus. Simulated septoplasty performed 20 Wistar rats. hippocampus dentate gyrus (DG) were examined, which number DN determined at 2, 4 6 days after surgery. Compared with control group (n = 5), increased experimental ani...

let $r$ be a commutative ring with identity. an ideal $i$ of a ring $r$is called an annihilating ideal if there exists $rin rsetminus {0}$ such that $ir=(0)$ and an ideal $i$ of$r$ is called an essential ideal if $i$ has non-zero intersectionwith every other non-zero ideal of $r$. thesum-annihilating essential ideal graph of $r$, denoted by $mathcal{ae}_r$, isa graph whose vertex set is the set...

Background and Objectives Regular aerobic exercise improves learning, memory, cognitive Synaptic Plasticity in Alzheimer’s disease (AD) patients. The aim of this study was to evaluate the levels calcineurin Ca2+/calmodulin-dependent protein kinase II mRNA after four weeks training exercises before AD induction hippocampus male Wistar rats. Subjects Methods Thirty 8-week-old rats with an average...

The hippocampus is located in the medial temporal lobe and is a part of the forebrain. It plays a critical role in formation of declared memories. The hippocampus is banana­-shaped and communicates with all parts of neocortex. Reptiles and birds have structures like hippocampus that potentially serve as navigation functions. During the mammalian evolution, the neocortex has a large expansio...

Treatment of brain cancer, glioma, can cause cognitive impairment as a side-effect, possibly because it disrupts the integrity hippocampus, structure vital for normal memory. Radiotherapy is commonly used to treat but effects irradiation on are still poorly understood, and other biological have not been extensively studied. Here, we exposed healthy adult male rats moderate-dose head. We found n...

background: hippocampal damages, which are accompanied by inflammation, are among the main causes of epilepsy acquisition. we previously reported that chronic intracerebroventricular (i.c.v.) injection of lipopolysaccharide (lps) modulates epileptogenesis in rats. there is a network of gap junction channels in the hippocampus that contribute to epileptogenesis. gap junction channels are formed ...

seizure may occur after mild traumatic brain injury (tbi), and the severity of tbi can be considered the most crucial factor for an increased risk of recurring seizures as well as for the development of posttraumatic epilepsy. however, the effect of seizures in epileptogenesis after mild tbi cannot yet be accurately confirmed. this study was designed to determine whether mild tbi increases seiz...

the effect of endogenous serotonin on long-term potentiation (ltp) in region cai was studied by blocking 5-ht2 receptors with ketanserin in rat hippocampal slices. such a block significantly en-hanced long-term potentiation of the cai population spike induced by high frequency stimulation of the schaffer collateral/ commissural pathway. this implies that serotonin acts on 5-ht2 receptors in cai...