The molecular mechanisms involved in the hepatic tropism of hepatitis C virus (HCV) have not been identified. We have shown previously that liver-expressed C-type lectins L-SIGN and DC-SIGN bind the HCV E2 glycoprotein with high affinity (Lozach, P. Y., Lortat-Jacob, H., de Lacroix de Lavalette, A., Staropoli, I., Foung, S., Amara, A., Houles, C., Fieschi, F., Schwartz, O., Virelizier, J. L., A...

Reports of malignant tumors of the fingers have appeared frequently in medical literature, but most of these have described cases of sarcoma, melanosarcoma, or carcinoma secondary to roentgen, radium, or acid burns. Primary carcinoma of the fingers with no demonstrable etiological factor has rarely been reported. . If chronic irritation is considered an important and definite factor in the orig...

reperfusion on transmural myocardial remodeling in dogs. Circulation 1995;91: 1143–1153. 20. Homans DC, Pavek T, Laxson DD, Bache RJ. Recovery of transmural and subepicardial wall thickening after subendocardial infarction. J Am Coll Cardiol 1994;24: 1109–1116. 21. Korinek J, Wand J, Sengupta PP, Miyazaki C, Kjaergaard J, McMahon E, Abraham TP, Belohlavek M. Two-dimensional strain—a Doppler-ind...

Lan Xia is Assistant Professor of Marketing, Bentley College (e-mail: [email protected]). Kent B. Monroe is J.M. Jones Professor of Marketing, Department of Business Administration, University of Illinois, Champaign (e-mail: [email protected]). Jennifer L. Cox is Associate Brand Manager, John Deere Worldwide Commercial & Consumer Equipment (e-mail: [email protected]). The authors gratef...

Cytotoxic fractions obtained by purification of the ethanolic extract of Anasterias minuta contain sulfated hexasaccharide glycosides. These compounds show antifungal activity against Cladosporium cucumerinum. Introduction Extracts and saponins isolated from starfish show a broad spectrum of biological effects: cytotoxic, hemolytic, antifungal and antiviral activities [1]. Although a high numbe...

A BRIEF HISTORY OF MEDICINE IN MASSACHUSETTS. By Henry R. Viets, M.D., (Fellow of Massachusetts Medical Society). Boston and New York: Houghton, Mifflin Company, I930, Xiv + I94 pp. One of the salutary signs of the growing interest in the history of medicine is the recent appearance of a large number of histories of medicine devoted to a given locality-a country, a state, a town, or even a hosp...

The position of mevalonic acid and isopentenyl pyrophosphate (3 methylbut 3 enyl pyrophosphate) as key intermediates in the biosynthesis of isoprenoid compounds is now firmly established, as also is the route by which mevalonic acid is converted into isopentenyl pyrophosphate. This transformation occurs through three ATP-dependent steps with the intermediate formation of mevalonate 5-phosphate ...

We propose that two psychological dimensions, one relevant to relationships and group life (communion, C) and the other to skill acquisition, talent, and accomplishment (agency, A), aid people in interpreting their social worlds. Moreover, our analysis demonstrates the privileged nature of the C dimension and its relative stability compared to the A dimension across contexts and cultures. In St...

This research examined an attempt to facilitate racial integration by populating squads (i.e., workgroups) in a police academy with mixes of recruits that reflected the racial demographics of the larger cohort. This was part of the social infrastructure of the academy. Additionally, a fixed seating arrangement was considered as a second element of academy infrastructure capable of impacting rac...

Identification of network linkages through direct observation of human interaction has long been a staple of network analysis. It is, however, time consuming and labor intensive when undertaken by human observers. This paper describes the development and validation of a two-stage methodology for automating the identification of network links from direct observation of groups in which members ar...