نتایج جستجو برای: hoxa10
تعداد نتایج: 288 فیلتر نتایج به سال:
BACKGROUND The DNA demethylating agent 5-aza-2'-deoxycytidine (5-aza-CdR) incorporates into DNA and decreases DNA methylation, sparking interest in its use as a potential therapeutic agent. We aimed to determine the effects of maternal 5-aza-CdR treatment on embryo implantation in the mouse and to evaluate whether these effects are associated with decreased levels of DNA methyltransferases (Dnm...
Endometrial receptivity is highly correlated with the implantation rate, whereby in Indonesia, rate among vitro fertilisation programs still low, around 19.3%. Antagonist ovarian stimulation protocol can disrupt physiological endocrine milieu by presence of supra-physiological levels estrogen and progesterone, both which are thought to indirectly affect expression adhesion molecule cells. Homeo...
Endometriosis is a gynecologic disorder characterized by the presence of viable, extrauterine endometrial tissue, predominantly on the ovary and pelvic peritoneum (1−3). Typical symptoms consist of pelvic pain, dysmenorrhea, and infertility (1, 2). This condition takes place only in women of menstrual age, can grow or bleed cyclically and may cause adhesions (1, 2). Endometriosis represents a w...
To understand effects of Bisphenol-A (BPA) exposure on the reproductive organ across generations, we analyzed morphology of the uterus and ovary, and the methylation pattern of HOXA10 gene of the 2(nd) generation. Pregnant mice (F0) were treated with sc injection of BPA in sesame oil at various doses of 0-1,000 mg/kg Bwt on days 12-16 of gestation. Their offspring (F1) were bred by foster mice,...
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