نتایج جستجو برای: hsct
تعداد نتایج: 3502 فیلتر نتایج به سال:
To specify the incidence and risk factors for secondary autoimmune diseases (ADs) after HSCT for a primary AD, we retrospectively analyzed AD patients treated by HSCT reported to EBMT from 1995 to 2009 with at least 1 secondary AD (cases) and those without (controls). After autologous HSCT, 29 of 347 patients developed at least 1 secondary AD within 21.9 (0.6-49) months and after allogeneic HSC...
Based on the principle that immune ablation followed by HSC-mediated recovery purges disease-causing leukocytes to interrupt autoimmune disease progression, hematopoietic stem cell transplantation (HSCT) has been increasingly used as a treatment for severe autoimmune diseases. Despite clinically-relevant outcomes, HSCT is associated with serious iatrogenic risks and is suitable only for the mos...
Currently, hematopoietic stem cell transplantation (HSCT) is the only curative option for patients with beta-thalassemia major, but liver iron overload in these patients will not decrease and hepatic fibrosis may still progress despite successful HSCT. Liver biopsy samples were taken from 14 patients (Out of 25 patients) who underwent HSCT. All patients met three criteria: negative HCV antibody...
We evaluated short term changes in thyroid function in patients who underwent hematopoietic stem cell transplantation (HSCT) during childhood. And we attempted to find clinical and treatment risk factors for thyroid dysfunction during 3 months after HSCT We studied 170 patients (102 boys and 68 girls) who underwent HSCT at the Catholic HSCT center from January, 2004 to December, 2009. Patients ...
The clinical and biological relevance of a paraprotein that newly arises after allogeneic hematopoietic stem cell transplantation (allo-HSCT) in non-myeloma patients is unknown. In this study, the incidence, the course, and the clinical impact of paraproteins found after allo-HSCT were investigated in a cohort of 383 non-myeloma patients. Paraproteinemia after allo-HSCT was more frequent (52/38...
The first hematopoietic stem cell transplantation (HSCT), the replacement of the hematopoietic system, by hematopoietic stem cells from the patient (autologous HSCT) or from another person (allogeneic HSCT), was performed almost 45 years ago. Today autologous HSCT is used to bridge hematopoietic failure after high dose chemotherapy for the treatment of selected hematopoietic and non-hematopoiet...
BACKGROUND The incidence of symptomatic venous thromboembolism (VTE) following hematopoietic stem cell transplantation (HSCT) is not well described, particularly with increased use of ambulatory care in the transplant setting. METHODS A retrospective analysis involving 589 patients (382 autologous HSCT, 207 allogeneic HSCT) undergoing transplantation between 2000 and 2005 in a single Canadian...
PURPOSE/OBJECTIVES To test whether a widely used model of adjustment to illness, the self-regulatory model, explains the patterns of distress during acute hematopoietic stem cell transplantation (HSCT). According to the model, perceptions of HSCT, coping, and coping appraisals are associated with distress. . DESIGN Longitudinal, correlational. . SETTING The Centre for Clinical Haematology a...
Unrelated donor (URD) is an acceptable source of stem cell grafts for adults. With the growth in available URD, improved human leukocyte antigen (HLA) typing technology and better understanding of HLA matching, the number of URD haematopoietic stem cell transplantation (URD-HSCT) is increasing dramatically in recent years. Peripheral blood stem cells have surpassed bone marrow as the preferred ...
the introduction and evolution of hematopoietic stem cell transplantation (hsct) could be traced back to 1950s, to the studies on interactions among irradiation, covering spleen and bone marrow from it and injection of bone marrow cells. today, hsct is considered a well-established, effective and promising means of therapy for various malignant and non-malignant medical conditions, both in chil...
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