نتایج جستجو برای: ht3a

تعداد نتایج: 167  

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 2005
Kimberly J Dougherty B Anne Bannatyne Elzbieta Jankowska Piotr Krutki David J Maxwell

Modulatory actions of a metabotropic 5-HT1A&7 membrane receptor agonist and antagonist [(+/-)-8-hydroxy-2-(di-n-propylamino)-tetralin; N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl) cyclohexane-carboxamide] and an ionotropic 5-HT3 membrane receptor agonist and antagonist [2-methyl-serotonin (2-Me 5-HT); N-(1-azabicyclo[2.2.2]oct-3-yl)-6-chloro-4-methyl-3-oxo-3,4-dihydro-2H-1,4-b...

Journal: :Biochimica et Biophysica Acta (BBA) - Biomembranes 2013

2013
AJ Thompson SCR Lummis

The 5-HT3B subunit was first cloned in 1999, and co-expression with the 5-HT3A subunit results in heteromeric 5-HT₃AB receptors that are functionally distinct from homomeric 5-HT₃A receptors. The affinities of competitive ligands at the two receptor subtypes are usually similar, but those of non-competitive antagonists that bind in the pore often differ. A competitive ligand and allosteric modu...

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