نتایج جستجو برای: human epidermal growth factor receptor 2 her 2
تعداد نتایج: 5073461 فیلتر نتایج به سال:
Epidermal growth factor receptor as a potential therapeutic target in triple-negative breast cancer.
BACKGROUND No proven targeted therapy is currently available for the treatment of triple-negative breast cancer (TNBC). Epidermal growth factor receptor (EGFR) is frequently overexpressed in TNBC. We studied the activity of EGFR antagonists alone, and in combination with chemotherapy, in TNBC cell lines. MATERIALS AND METHODS EGFR and phosphorylated EGFR were measured by enzyme-linked immunos...
We explored the feasibility of designing retroviral vectors that can target human breast cancer cells with characteristic receptors via ligand-receptor interaction. The ecotropic Moloney murine leukemia virus envelope was modified by insertion of sequences encoding human heregulin. Ecotropic virus, which normally does not infect human cells, when pseudotyped with the modified envelope protein n...
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