This review discusses the increasing potential of chitosan nanocomposites as viable materials capable targeting these debilitating factors. focuses on various techniques used to process and their mechanical properties. Chitosan are regarded highly effective antimicrobials for treatment chronic wounds. nanocomposites, such chitosan/polyethylene oxide/silica/ciprofloxacin, demonstrate efficient a...

We have previously reported that seventy percent ethanol extract of Chrysanthemum indicum Linne (CIE) strongly reduces Epstein-Barr virus (EBV)-transformed lymphoblastoid cell line (LCL) survival by inhibiting virus-encoded latent infection membrane protein 1 (LMP1)-induced NF-κB activation. To identify an active compound(s) in CIE that inhibits LMP1-induced NF-κB activation, activity-guided fr...

background: erythropoietin (epo) is a glycoprotein hormone function to regulate the production of red blood cells. deficiency of epo is known to cause anemia in chronically infected renal patients and they require regular blood transfusion. availability of recombinant epo has eliminated the need for blood transfusion and now it is extensively used for the treatment of anemia. glycosylation of e...

In this study, an attempt has been made to synthesize nanoemulsions using Trachyspermum ammi tincture. The nanoemulsion specifications are characterized by TEM, DLS, and zeta potential. anti-tumour cell toxicity effects of the biosynthesized evaluated chorioallantoic membrane (CAM) MTT assays, respectively. For CAM test, length number blood vessels around gelatine sponge. According DLS analysis...

Quinoline derivatives have been reported to possess multi-therapeutic potential owing the manifestations of different pharmacological effects. The current research work describes about design and synthesis a series novel benzoquinoline analogues with an objective evaluate their antiproliferative structure–activity relationship against colon, breast hepatocellular cancers. Upon synthesis, all de...

The KCL017 human embryonic stem cell line was derived from an embryo donated for research that carried an autosomal dominant mutation affecting splicing site of the VHL gene encoding von Hippel-Lindau tumor suppressor E3 ubiquitin protein ligase (676+3A>T). The ICM was isolated using laser microsurgery and plated on γ-irradiated human foreskin fibroblasts. Both the derivation and cell line prop...

Background: In this study, the effects of three structural analogues of adenosine upon proliferation of human tumor cells were investigated. Previous research showed a cytotoxic effect of adenosine via A3 receptor and A1 receptor and sometimes this effect was receptor independent. The researches showed a differential cytotoxic effect of adenosine and its A3 agonists on cancerous cells, while ot...