objective: pulp and periodontal tissues are well-known sources of mesenchymal stem cells (mscs) that provide a promising place in tissue engineering and regenerative medicine. the molecular mechanisms underlying commitment and differentiation of dental stem cells that originate from different dental tissues are not fully understood. in this study, we have compared the expression levels of pluri...

multipotent mesenchymal stromal cells or mesenchymal stem cells (mscs) are mainly isolated from bone marrow or fat tissue. because of their potential of multilineage differentiation towards bone, cartilage and fat tissue, they were initially evaluated to develop innovative strategies for tissue engineering applications. more recently, they have gained interest based on their immunomodulatory pr...

objective(s)para-nonylphenol (p-np) is used in many industries and our previous study showed that p-np causes a reduction in rats bone marrow mesenchymal stem cells (mscs) viability. the aim of this study was to investigate the effect of p-np on osteogenic differentiation of mscs.materials and methodsmscs were isolated and expanded to 3rd passage, then cultured in dmem supplemented with osteoge...

objective: in this study we introduced an rgd-containing peptide of collagen iv origin that possesses potent cell adhesion and proliferation properties. this peptide was immobilized on a nanofibrous polycaprolactone/gelatin scaffold after which we analyzed human bone marrow-derived mesenchymal stem cells (hbmscs) adhesion and proliferation on this peptide-modified scaffold. methods: nanofibrous...

background: bone marrow mesenchymal stem cells (mscs) are one of the undifferentiated multipotential cell sources of human body. methods: mscs have the capacity to form a variety of cell types, especially chondrocytes and osteocytes. learning about responses of mscs to external milieu and chemical factors such as ph could recommend new approaches for preparation of suitable scaffolds for bone a...

ex vivo expansion of human umbilical cord blood cells (hucbc) is explored by several investigators to enhance the repopulating potential of hucbc. the proliferation and expansion of human hematopoietic stem cells (hsc) in ex vivo culture was examined with the goal of generating a suitable clinical protocol for expanding hsc for patient transplantation. using primary human mesenchymal stem cells...

  Introduction: The field of stem cell biology and regenerative medicine is rapidly moving toward translation to clinical practice. Stem cell therapy seems to be a new treatment option for some diseases. So, tracking the distribution of stem cells is crucial to their therapeutic use. Based on this fact we labeled human mesenchymal stem cells (MSCs) with 111...

tissue engineering based on the adipose derived stem cells  promote a strong strategy to propagation of bone, cartilage and fat tissues in the three-dimensional scaffolds, fabricated by combining biological materials with suitable and appropriate growth factors.  in this study, a peo scaffold was used to show that mesenchymal stem cells can attach well; the aim of this study was the investigati...

abstractbackground: fetal bovine serum (fbs) is widely used in cell culture laboratories,risk of zoonotic infections and allergic side effects create obstacles for its use inclinical trials. therefore, an alternative supplement with proper inherent growthpromotingactivities is demanded.objective: to find fbs substitute, we tested human umbilical cord blood serum(hucs) for proliferation of human...

background: due to increasing clinical demand for adipose tissue, a suitable cell for reconstructive adipose tissue constructs is needed. in this study, we investigated the ability of human endometrial-derived stem cells (enscs) as a new source of mesenchymal stem cells to differentiate into adipocytes. enscs are the abundant and easy available source with no immunological response, for cell re...