Hallux valgus (HV) is a common deformity characterized by progressive lateral deviation of the great toe at the first metatarsophalangeal joint (1 MTPJ). It commonly associates with a painful overlying soft-tissue prominence, the “bunion”. A recent systematic review estimated the prevalence of HV to be 23% in adults aged 18 to 65 years. It becomes more frequent with increasing age and is more p...

1-Vinylcycloalkenes undergo highly regio- and enantioselective (>98% ee) 1,4-hydrovinylation (HV) when treated with ethylene (1 atm) at room temperature in the presence of [(S,S)-2,4-bis-diphenylphosphinopentane (BDPP)]CoCl(2) (0.05 equiv) and methylaluminoxane. The minor 1,2-HV products, seen only in 1-vinylcyclohexene (~15%) and 1-vinylcycloheptene (2%), are formed as racemic mixtures. The co...

Hippocampal atrophy is observed with ageing and age-related neurodegenerative disease. Identification of the genetic correlates of hippocampal volume (HV) and atrophy may assist in elucidating the mechanisms of ageing and age-related neurodegeneration. Using two community cohorts of older Caucasians we estimated the heritability of HV and examined associations of HV with previously identified s...

The pharmacological profile of a new alpha-1 adrenoceptor antagonist, alpha-ethyl-3,4,5-trimethoxy-alpha-(3-((2-(2-methoxyphenoxy)ethyl)amino) propyl) benzene-acetonitrile fumarate (HV-723), was studied in vitro. In dog mesenteric arteries, HV-723, prazosin and yohimbine competitively inhibited noradrenaline-induced contraction: the pA2 value of HV-723 (9.37) was apparently larger than that of ...

SAK-HV is an anti-atherosclerosis recombinant fusion protein developed by our lab. Our study determined that SAK-HV promoted macrophage proliferation, of which the mechanism was explored by both RAW264.7 cells and primary macrophages. Mass spectrometric analysis and co-immunoprecipitation were combined to screen the SAK-HV-interacting proteins in RAW264.7 cells. Confocal microscopy was adopted ...

Compatible rhizobia strains are essential for nodulation and biological nitrogen fixation (BNF) of hairy vetch (Vicia villosa Roth, HV). We evaluated how past HV cultivation affected nodulation and BNF across host genotypes. Five groups of similar HV genotypes were inoculated with soil dilutions from six paired fields, three with 10-year HV cultivation history (HV+) and three with no history (H...

This paper extends the existing transmission and capacity analysis in order to investigate the broadband potential of overhead high-voltage/broadband over power lines (HV/BPL) connections where a single repeater is additively deployed between their existing transmitting and receiving ends (overhead HV/BPL connections with two-hop repeater system). The contribution of this paper is threefold. Fi...

Let K be a compact Lie group acting on a finite dimensional Hermitian vector space V via some unitary representation. Now K acts by automorphisms on the associated Heisenberg group HV = V × R and we say that (K,HV ) is a Gelfand pair when the algebra LK(HV ) of integrable K-invariant functions on HV commutes under convolution. In this situation an application of the Orbit Method yields a inject...

CAEBV: Chronic active Epstein-Barr virus infection DM: Dermatomyositis EBV: Epstein-Barr virus HLA: Human leukocyte antigen HV: Hydroa vacciniforme INTRODUCTION Atypical hydroa vacciniforme (HV) is a rare vesiculopapular eruption reported mainly in patients from Asia and Latin America and presents with similar but more severe cutaneous manifestations than classic HV. In addition, systemic findi...