Cationic porphyrin-anthraquinone hybrids bearing peripheral substituents, either pyridine, imidazole, or pyrazole rings have been investigated for their binding mode to DNA duplexes. The four kinds of DNA duplexes were used, which represent intercalation and groove binding modes. AutoDock 4.2 was used to dock nine hybrid compounds to four DNA duplexes, while monitoring of conformational changes...

Hybrid antibodies possessing one binding site for the toxic lectin ricin and a companion site directed against human immunoglobulm were constructed in vitro. This bifunctional re agent specifically attached to human lymphocyte surface immunoglobulin determinants and, thus situated, could simulta neously capture ricin molecules or its toxic A chain. Attachment of these components to the cell was...

Hybrid antibodies possessing one binding site for the toxic lectin ricin and a companion site directed against human immunoglobulin were constructed in vitro. This bifunctional reagent specifically attached to human lymphocyte surface immunoglobulin determinants and, thus situated, could simultaneously capture ricin molecules or its toxic A chain. Attachment of these components to the cell was ...

The introduction of carbon-fibre reinforced plastics in load bearing automotive structures provides a great potential to reduce vehicle weight and fuel consumption. To enable the manufacture and assembly of composite structural parts, reliable and cost-effective joining technologies must be developed. This thesis addresses several aspects of joining and load introduction in carbon-fibre reinfor...

Abstract—The design and implementation of the hybrid control method for a three-pole active magnetic bearing (AMB) is proposed in this paper. The system is inherently nonlinear and conventional nonlinear controllers are a little complicated, while the proposed hybrid controller has a piecewise linear form, i.e. linear in each subregion. A state-feedback hybrid controller is designed in this stu...