This study describes a facile two-step approach to modify the surface of nanoparticles, thereby imparting a core-shell structure to the system. The core consists of magnetic nanoparticles and the shell is composed of thermoresponsive hydroxypropyl cellulose, using a coupling agent to covalently bind the core to the shell. Hydroxypropyl cellulose is known for its biocompatibility and biodegradab...

in this study, magnetic iron oxide nanoparticles (fe3o4) with the size range of 20-30 nm were prepared by the modified controlled chemical co-precipitation method from the solution of ferrous/ferric mixed salt-solution in alkaline medium. in this process polyethylene glycol was used as a surfactant to prevent the solution from agglomeration. the prepared magnetic nanoparticles were characterize...

fe3o4 nanostructures were synthesized via a facile hydrothermal reaction. the effect of various surfactants such as cationic and anionic on the morphology of the product was investigated. magnetic nanoparticles were added to poly styrene (ps) for preparation of magnetic nanocomposite. nanostructures were then characterized using x-ray diffraction (xrd), scanning electron microscopy (sem) and fo...

Poly(lactic-co-glycolic acid) (PLGA) nanoparticles (NPs) incorporating quantum dots (QDs), superparamagnetic iron oxide nanoparticles (SPIONs) and gold (Au) NPs for neutrophil labeling were fabricated via the w/o/w double emulsion method. QDs and SPIONs were entrapped in the PLGA core during emulsification while Au NPs were assembled on top of the PLGA NPs via electrostatic interactions. Transm...

BACKGROUND Advances in nanostructure materials are leading to novel strategies for drug delivery and targeting, contrast media for magnetic resonance imaging (MRI), agents for hyperthermia and nanocarriers. Superparamagnetic iron oxide nanoparticles (SPIONs) are useful for all of these applications, and in drug-release systems, SPIONs allow for the localization, direction and concentration of d...

n-sodium acrylate-o-carboxymethyl chitosan [cmch-g-paa(na)] bound fe3o4 nanoparticles were developed as a novel magnetic nanoparticles with an ionic structure that can be potentially used in many fields. cmch-g-paa (na) was obtained by grafting of sodium polyacrylate on o-carboxymethyl chitosan, which is an amphiphilic polyelectrolyte with the biocompatibility and biodegradability properties. a...

Luminescent hybrid nanoparticles with a paramagnetic Gd2O3 core were applied as contrast agents for both in vivo fluorescence and magnetic resonance imaging. These hybrid particles were obtained by encapsulating Gd2O3 cores within a polysiloxane shell which carries organic fluorophores and carboxylated PEG covalently tethered to the inorganic network. Longitudinal proton relaxivities of these p...

sio2-coated cobalt ferrite (cofe2o4) nanoparticles were obtained by the hydrolysis of tetraethylorthosilicate in the presence of cofe2o4 nanoparticles in co-precipitation. the effects of sio2coating on the magnetic properties of cofe2o4 nanoparticles were investigated. the structural, morphological and magnetic properties of as-prepared sample were characterization by x-ray diffraction (xrd), f...

Background Glioblastoma is the most devastating primary brain tumor of the central nervous system in adults. Magnetic nanocarriers may help not only for a targeted delivery of chemotherapeutic agents into the tumor site but also provide contrast enhancing properties for diagnostics using magnetic resonance imaging (MRI). Methods Synthesized hybrid chitosan-dextran superparamagnetic nanopartic...