Familial Mediterranean fever (FMF), affecting people of Mediterranean origin, is an endemic and sometimes problematic disease because of colchicine resistance/intolerance, with relative lack of treatment alternatives, and disease- or treatment-related issues, such as subfertility. Anakinra, being a rational and effective treatment alternative, has no conclusive human pregnancy data. Here we rep...

OBJECTIVE: To review the technique and results of falloposcopy, and the classification and management of fallopian tube disease. DATA SOURCES: Medline and non-Medline search of the relevant English literature, and personal experience. STUDY SELECTION: Studies involving the use of falloposcopy to assess tubal status were selected for review. DATA EXTRACTION: The procedure of falloposcopy and its...

congenital and acquired abnormalities of the reproductive tract of female sheep resulting in subfertility,infertility or sterility cannot easily be detected by routine clinical examination. morphopathologicalabnormalities of the reproductive tract of ewes were studied by examining a total of 739 genital tracts inabattoirs of fars province, iran. from these, the 648 non-pregnant genitalia were e...

Obesity has become a health problem in affluent societies, but few studies have investigated its effect on subfertility. Previous studies were based on select groups of women, focused mainly on ovulatory dysfunctions, and yielded controversial results. The authors evaluated the effect of body mass index on delayed conception by using a European population-based survey of pregnant women from fiv...

BACKGROUND Among women with unexplained infertility, 28% to 55% of patients with galactorrhea are normoprolactinemic. Bromocriptine, a common treatment for infertile women with hyperprolactinemia, has been used in the treatment of unexplained subfertility in women with galactorrhea and normal prolactin; however, its effectiveness and safety profile have never been determined. OBJECTIVE The ai...

BACKGROUND/OBJECTIVES It has been suggested that subfertility and testicular cancer share genetic and environmental risk factors. We studied both subfertility and the strongest known testicular cancer susceptibility gene, the c-KIT ligand (KITLG), whose pathway is involved in spermatogenesis. METHODS The EPSAM case-control study is comprised of testicular cancer patients from the Province of ...

Classically, the diagnosis of adenomyosis has only been possible on a hysterectomy specimen, usually in women in their late fourth and fifth decades, and, therefore, evaluating any relationship with infertility was simply not possible. As a consequence, to this day, no epidemiologic data exists linking adenomyosis to a state of subfertility. Today, new imaging techniques have enabled a noninvas...

BACKGROUND With the occasional reports of unexpectedly poor ovarian response to controlled ovarian hyperstimulation (COH) for IVF in young normally cyclic women in mind, we studied age-related ovarian response to COH in a group of women who underwent standard IVF. METHODS Ovarian response to COH was defined as the number of follicles > or = 14 mm on the day of hCG administration. Ovarian resp...

BACKGROUND Intrauterine insemination (IUI) could become preferred to more invasive and expensive techniques of assisted reproduction therapy (ART) and should be offered as the first choice in cases with no female factors and mild male factor subfertility. However, developing countries and especially their rural areas often lack the necessary equipment and laboratory facilities. OBJECTIVE To d...