Anti-cytomegalovirus (anti-CMV) hyperimmune globulin (HIG) has demonstrated efficacy in preventing CMV disease in solid-organ transplant patients as well as congenital disease when administered to pregnant women. To identify the neutralizing component of cytomegalovirus hyperimmune globulin (CMV-HIG), we performed serial depletions of CMV-HIG on cell-surface-expressed CMV antigens as well as pu...

This paper investigates the relation between immunity and hardness in exponential time. The idea that these concepts are related originated in computability theory where it led to Post’s program, and it has been continued successfully in complexity theory [9, 13, 20]. We study three notions of immunity for exponential time. An infinite set A is called • EXP-immune, if it does not contain an inf...

We read with concern the article on passive hyperimmune therapy in the treatment of acquired immunodeficiency syndrome (AIDS).’ In this report, the investigators attempted to show the efficacy of plasma taken from asymptomatic human immunodeficiency virus (H1V)-positive donors with antibody to HIV on the clinical course of AIDS patients. The investigators set up four requirements to establish e...

We explore the computational strength of the hyperimmunefree Turing degrees. In particular we investigate how the property of being dominated by recursive functions interact with classical computability notions such as the jump operator, relativization and effectively closed

We read with concern the article on passive hyperimmune therapy in the treatment of acquired immunodeficiency syndrome (AIDS).’ In this report, the investigators attempted to show the efficacy of plasma taken from asymptomatic human immunodeficiency virus (H1V)-positive donors with antibody to HIV on the clinical course of AIDS patients. The investigators set up four requirements to establish e...

BACKGROUND American tegumentary leishmaniasis (ATL) is endemic in Latin America, where Brazil has over 27 thousand cases per year. The aim of the present study was to develop an immunohistochemical method (IHC) for ATL diagnosis. For this purpose, we used serum from a dog naturally infected with Leishmania (L) infantum (canine hyperimmune serum) as the primary antibody, followed by a detection ...

This study evaluated the prophylactic effectiveness of hyperimmune plasma (HIP) as an aid in the prevention of pneumonia caused by experimental infection with Rhodococcus equi. Thirty neonatal foals were administered R. equi HIP or saline at 2 days of age and were infected with virulent R. equi at 7 days. All foals developed signs or symptoms of respiratory disease. Radiographic scores on day 2...