نتایج جستجو برای: hyperlipoproteinemia
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Hyperlipoproteinemia contributes both to kidney disease progression and the development of atherosclerosis. Elevated high density lipoprotein cholesterol and apolipoprotein A-I (apoA-I) serum levels are independent factors protective against the atherosclerotic process. We examined the effects in a transgenic rat model of human apoA-I expression on the hyperlipoproteinemia and edema after purom...
Familial hypercholesterolemia, a form of primary hyperlipoproteinemia, is an autosomal dominant disorder characterized by an increase in serum LDL cholesterol concentrations. Multiple types of xanthomas occur, such as tendinous, tuberous, subperiosteal, and xanthelasma. Intertriginous xanthomas are rare, but if present are pathognomonic in this disorder. We report a patient with multiple xantho...
From the Clinical Physiology Unit, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, Mich. This study was supported in part by grants from the Michigan Heart Association and from the National Institutes of Health (CD OClO811. Manuscript received April 28, 1969, accepted November 7, 1969. * Present address: A. 8. Hassle, Fack. Goteborg 5, Sweden. t U. S. Army Med...
AIM We report a case of bevacizumab-associated hyperlipoproteinemia in a patient with advanced breast cancer. CASE SUMMARY A 57-year-old woman with advanced invasive-ductal breast cancer was administered bevacizumab from March 2008 to February 2009. Pretreatment laboratory showed borderline hypercholesterolemia (5.1 mmol/L, 197 mg/dL) and normal triglycerides (1.3 mmol/L, 115 mg/dL). Three mo...
Apolipoprotein E (apo E) plays a role in the regulation of the lipid metabolism of humans. Apo E, 229 amino acid polypeptide, is classified into three major isoform (E2, E3, E4) according to the differences of amino acid in position 112 and 158. In the normal population apo E3 isoform is most prevalent and apo E2 or E4 is frequently associated with hyperlipoproteinemia. To find out the frequenc...
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