Hypertrophic scars and keloids are a problem that mainly dermatologists and plastic surgeons encounter. Especially in the head and neck region, these lesions are conspicuous and not easy for patients to conceal. Patients typically present with cosmetic concerns, although hypertrophic scars and keloids can also cause pruritus, pain, or pressure. This article reviews various treatment modalities ...

Hypertrophic scars and keloids result from abnormal wound healing in predisposed individuals. They occur within months of cutaneous trauma (surgical wounds, piercing, lacerations) or inflammation (acne, folliculitis, vaccination site). They have rarely been reported after chickenpox. Herein we report a dramatic case in a 4-year-old black girl and discuss the issues related to the management of ...

Excessive scars, including keloids and hypertrophic scars, result from aberrations in the process of physiologic wound healing. An exaggerated inflammatory process is one of the main pathophysiological contributors. Scars may cause pain, and pruritis, limit joint mobility, and cause a range of cosmetic deformities that affect the patient's quality of life. Extensive research has been done on hy...

Hypertrophic scars are one of the most important complications in surgery due to their cosmetic and functional impairments. Previous studies in tissue fibrotic disorders have shown promising results by inhibiting the biological activity effect of Transforming Growth Factorbeta 1 (TGF-β1). The aim of the current study was to determine the clinical effect of the inhibition of TGF-β1 signaling in ...

Hypertrophic scars and keloids following aesthetic surgery, which ignite patient dissatisfaction, are difficult to handle. Intralesional cryosurgery for the treatment of such scars has been introduced. This study was designed to evaluate the efficacy of this technology in the treatment of such scars and to assess the reduction of dissatisfaction. Eleven scars (on 11 patients) were treated by in...

Keloids and hypertrophic scars are characterized by excessive deposition of dermal collagen with resultant scar tissue. This scar tissue is benign, non-contagious and sometimes accompanied by severe itching, sharp pains and changes in texture. In severe cases, it can affect movement of skin and may ulcerate. There are various lines of treatment of keloids and hypertrophic scars including nutrit...

background: results of various studies suggest that the hypertrophic and keloid scars are highly prevalent in the general population and are irritating both physically and mentally. objective: considering the variety of existing therapies, intense pulsed light (ipl) method along with corticosteroid injection was evaluated in treating these scars. materials and methods: 86 subjects were included...

Keloid and hypertrophic scars are a type of scarring pathology which is characterised by excess collagen deposition produced during the wound healing process. The mechanism by which this occurs is not understood and although hypertrophic scars can regress spontaneously, keloids do not, and currently no effective treatment exists. In this paper we hypothesise that nitric oxide, a free radical mo...