BACKGROUND Dental agenesis is the most common, often heritable, developmental anomaly in humans. Mutations in MSX1, PAX9, AXIN2 and the ectodermal dysplasia genes EDA, EDAR and EDARADD have been detected in familial severe tooth agenesis. However, until recently, in the majority of cases (∼90%) the genetic factor could not be identified, implying that other genes must be involved. Recent insigh...

The simultaneous occurrence of hypodontia and supernumerary teeth in the same individual is termed 'concomitant hypo-hyperodontia' (CHH). There appears to be a correlation between CHH and some syndromes, but this anomaly is very rare in the general population. The aim of this study was to investigate the frequency of CHH in a large sample of non-syndromic orthodontic patients. The records of 21...

OBJECTIVE The aim was to evaluate the prevalence and distribution of tooth number anomalies in a Turkish subpopulation. MATERIALS AND METHODS A population of 2722 patients (1532 females and 1190 males; mean age, 12.33 ± 2.5 years) was retrospectively examined to determine the prevalence and distribution of the hypodontia, oligodontia, and hyperdontia using panoramic radiographs. All permanent...

The purpose of this retrospective study was to determine the prevalence of hypodontia and associated dental anomalies in patients undergoing orthodontic treatment in Brasília, Brazil, over a 2 year period (1998-2000). The records of 1049 orthodontic patients between 10 and 15.7 years of age (507 males and 542 females) from 16 orthodontic clinics were analysed. Descriptive statistics were perfor...

BACKGROUND Even though tooth agenesis is the most common developmental anomaly of the human dentition, its genetic background and pathogenic mechanism(s) still remain poorly understood. Syndromic and isolated forms of hypodontia have been described and can occur sporadically or in families. OBJECTIVES We describe and analyse the hypo-/oligodontia phenotype variations in families. The index pa...

Prevalence of anomalies of deciduous teeth has been analyzed in the general population of Zagreb preschool children. The sample comprised 2,987 children from 3 to 6 years of age (1,582 boys and 1,405 girls). Hypodontia was found in 0.47%, hyperdontia in 0.10%, and double teeth in 0.43% of total sample. Total prevalence of all anomalies in the sample was 1.0%. The sample for the analysis of perm...

INTRODUCTION Hypodontia is the most frequent developmental anomaly of the orofacial complex, and its detection in prenatal ultrasound may indicate the presence of congenital malformations, genetic syndromes and chromosomal abnormalities. To date, only a few studies have evaluated the histological relationship of human tooth germs identified by two-dimensional (2D) ultrasonography. In order to a...

Hypodontia can be defined as the non-formation of one or more teeth during the developmental period. Mutation in several genes related to tooth formation has previously been correlated with cancer. Regarding the ovarian cancer, there are few studies that associate the presence of hypodontia with ovarian cancer. A systematic literature search was performed in PubMed and Scopus. In total, 385 pat...

OBJECTIVES The purpose of this study was to evaluate the clinical and radiographical characteristics of non-syndromic hypodontia and hyperdontia in the permanent dentition. STUDY DESIGN This study included 139 patients. Clinical and radiographical examinations were carried out by two examiners. Number and localization of missing or supernumerary teeth, and pathologies associated with the teet...

Kawasaki disease (KD) is a rare idiopathic infantile multi-organ vasculitis of medium-sized arteries that predominantly affects children younger than the age of 5 years. Besides the persistent fever of 5 or more days and among the typical criteria for the diagnosis of KD, a dentist may encounter oral manifestations such as “strawberry tongue”, red or dry fissured lip and oropharyngeal erythema....