The diagnosis and management of four cases of dermatological disorders, most of which are related to the endocrine disorder of androgen excess, are presented. Combined oral contraceptives (COCs) may be useful when well-tolerated hormonal therapy and/or when contraception is required. A female patient with androgenetic alopecia or female pattern balding, without underlying hyperandrogenism, was ...

Hirsutism is characterized by excessive growth of terminal hair in a male pattern. Idiopathic hirsutism (IH) is a common cause of hirsutism. Since there are few data demonstrating IH is associated with insulin resistance, we tried to assess various insulin sensitivity indices in lean IH and compare with healthy subjects. A cross-sectional study was performed in 71 lean (BMI between 20-25 kg/m(2...

AIM Hyperinsulinemia and insulin resistance are commonly seen in patients with hirsutism and polycystic ovary syndrome (PCOS), and are associated with cardiovascular disease risk. However, it is not yet known whether insulin-like growth factor I (IGF-I) and alanine transaminase (ALT) produced by the liver play roles in hyperinsulinemia and subclinical atherosclerotic process in patients with PC...

Background: Hirsutism is a common problem for which laser is being the treatment of choice. Several lasers with varying wavelengths, pulse durations, energy fluences and skin cooling systems, are currently used for hair removal. However, the ideal laser parameters and group of patients who respond better after treatment remain largely unknown. Objectives: A prospective study to evaluate the lon...

The biochemical abnormalities in patients with "idiopathic hirsutism" are imperfectly understood. The fractionation and measurement of urinary 17ketosteroids in these patients have been studied in several laboratories. It appears that this disorder is associated with increased production of an adrenal androgen which is reflected by increased excretion of urinary C1902 17-ketosteroids, in partic...

BACKGROUND Among classes of ovarian tumor, granulosa cell tumors are the least common. In approximately 10% of cases of granulosa cell tumor, androgen will be secreted which will present with hirsutism and hyperandrogenemia. We describe a woman with ovarian granulosa cell tumor who presented with hirsutism. CASE PRESENTATION A 50-year-old woman of Amhara ethnicity, para III, abortion I (induc...

AIM Many psychiatric disorders, including attention-deficit/hyperactivity disorder (ADHD), disruptive behavioral disorders, autism spectrum disorders, and some psychiatric characteristics, such as poor empathizing, are regarded to be related to elevated levels of androgens or androgen sensitivity. Thus, numerous studies have investigated the potential association between androgen-related physic...